Results 21 to 30 of about 24,241 (244)

Magnetic Resonance Spectroscopy of Hepatic Fat from Fundamental to Clinical Applications

Diagnostics, 2021
The number of individuals suffering from fatty liver is increasing worldwide, leading to interest in the noninvasive study of liver fat. Magnetic resonance spectroscopy (MRS) is a powerful tool that allows direct quantification of metabolites in tissue ...
Duanghathai Pasanta, Khin Thandar Htun, Jie Pan, Montree Tungjai, Siriprapa Kaewjaeng, Hongjoo Kim, Jakrapong Kaewkhao, Suchart Kothan   +7 more
doaj   +1 more source

Two cases of hemodynamic improvement by modulation of atrioventricular delay in cardiac operations

JA Clinical Reports, 2022
Background Symptomatic sick sinus syndrome is one of the indications for pacemaker implantation, and we have to consider to program the pacemaker to an asynchronous pacing mode during an operation. Case presentation We reported two cases with a pacemaker
Akiko Tomita-Kobayashi, Tomoko Fujimoto, Shoko Takada, Yuki Masuda, Akinobu Mizutani, Yukio Hayashi   +5 more
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Pentagalloyl Glucose-Targeted Inhibition of P-Glycoprotein and Re-Sensitization of Multidrug-Resistant Leukemic Cells (K562/ADR) to Doxorubicin: In Silico and Functional Studies

Pharmaceuticals, 2023
Combining phytochemicals with chemotherapeutic drugs has demonstrated the potential to surmount drug resistance. In this paper, we explore the efficacy of pentagalloyl glucose (PGG) in modulating P-gp and reversing multidrug resistance (MDR) in drug ...
Nathupakorn Dechsupa, Nopawit Khamto, Pornthip Chawapun, Sadanon Siriphong, Phattarawadee Innuan, Authaphinya Suwan, Thitiworada Luangsuep, Nichakorn Photilimthana, Witchayaporn Maita, Rossarin Thanacharttanatchaya, Padchanee Sangthong, Puttinan Meepowpan, Chatchanok Udomtanakunchai, Jiraporn Kantapan   +13 more
doaj   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Assessments of Medical Student’s Knowledge About Radiation Protection and Different Imaging Modalities in Jeddah, Saudi Arabia

International Journal of Biomedical Imaging
Conclusions: The assessments of medical students’ knowledge regarding radiation exposure in diagnostic modalities reveal a low level of confidence in their knowledge of ionizing radiation dose parameters. Furthermore, the mean scores on overall knowledge
Raghad Aljondi, Rahaf Alem, Rowa Aljondi, Abdulrahman Tajaldeen, Salem Saeed Alghamdi, Mohammed Majdi Toras   +5 more
doaj   +1 more source

Impact of Diabetes Mellitus and Ischaemic Heart Disease on the Blood Resistivity Index of Renal Arteries in Hypertensive Patients [PDF]

Journal of Clinical and Diagnostic Research, 2020
Introduction: Hypertension (HTN) is considered as one of the most common health problems. Doppler sonography plays an effective role in haemodynamic assessment of renal arteries in patients with essential HTN.
Moawia Gameraddin, Walaa Hidirbi, Suzan Abdelmaboud, Abdulaziz Qurashi, Sultan Alshoabi   +4 more
doaj   +1 more source

Radiological Technology for Targeted Radionuclide Therapy

Japanese Journal of Radiological Technology, 2020
Targeted radioisotope therapy (TRT) is a radiotherapy using radioisotope or drug incorporating it and has been used as a treatment for selectively irradiating cancer cells. In recent years, interest in TRT has increased due to improvements in radionuclide production technology, development of new drugs and imaging modalities, and improvements in ...
Kohei, Hanaoka, Noriaki, Miyaji, Hiroto, Yoneyama, Matsuyoshi, Ogawa, Takamasa, Maeda, Kenta, Sakaguchi, Takashi, Iimori, Hiroyuki, Tsushima   +7 more
openaire   +3 more sources

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Recent methods for the diagnosis and differentiation of ameloblastoma: a narrative review

All Life
Ameloblastoma is a benign but locally invasive tumour. Early diagnosis of ameloblastoma and formulating an appropriate treatment plan play a crucial role in reducing the postoperative recurrence rate.
Ke Hu, Xudong Zhang, Ruixue Chen, Xiangjun Li   +3 more
doaj   +1 more source