Results 171 to 180 of about 33,723,309 (265)

Shaping the Future of Pharmacology Education: Emerging Directions and International Initiatives From the Seventh International Union of Basic and Clinical Pharmacology Education Satellite Meeting. [PDF]

Pharmacol Res Perspect
Guilding C, Babey AM, Charles K, Cunningham M, Exintaris B, Fernandes LB, Hinton T, Karunaratne N, Koenig J, Mackay G, Restini C, Szarek JL, White PJ, Karpa K.   +13 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Assessment Fit for (More Than One) Purpose? Reconciling the Dual Purposes of Assessments in Competency-Based Health Professions Education. [PDF]

Perspect Med Educ
Ryan MS, Chen AMH, Nichol H, Huwendiek S, Richardson D, Kinnear B, Cheung WJ, Touchie C, Chou FC, Turner DA, Oswald A, As members of the International Competency-Based Health Professions Education Collaborative.   +11 more
europepmc   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Leveraging AI to Accelerate Competency-Based Education in the Health Professions. [PDF]

Perspect Med Educ
Lomis KD, Pusic MV, Warm E, Busari JO, Huwendiek S, Incoll IW, Lau LST, Boscardin CK, Chen JH, Tanaka P, Hauer KE, As members of the International Competency-Based Health Professions Educators Collaborative.   +11 more
europepmc   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Methodological quality of Campbell Systematic Reviews has improved over the past decade

Campbell Systematic Reviews, 2023
Yanfei Li, Omar Dewidar, Xiaoqin Wang, Elizabeth Ghogomu, Arpana Wadhwani, Ke Guo, Mina Ma, Victoria Barbeau, Bei Pan, Leenah Abdelrazeq, Zijun Li, Amjad Alghamyan, Liping Guo, Fatima Jahel, Junjie Ren, Mohamad Tarek Madani, Sarah Allam, Tarannum Hussain, Minyan Yang, Waleed Kojan, Xiuxia Li, Kehu Yang, Vivian Welch   +22 more
doaj   +1 more source

Age-Friendly Telegeriatrics: Evidence and a 5M-Based Framework for Hybrid Geriatric Care in Saudi Arabia. [PDF]

Cureus
Alsaad SM.
europepmc   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Rhythm-centred music interventions for motor coordination and rehabilitation: a scoping review of mechanisms, design principles, and technology-assisted assessment. [PDF]

J Rehabil Med
Song Y, Wei Y.
europepmc   +1 more source