Results 181 to 190 of about 4,155,604 (307)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Methodological quality of Campbell Systematic Reviews has improved over the past decade

Campbell Systematic Reviews, 2023
Yanfei Li, Omar Dewidar, Xiaoqin Wang, Elizabeth Ghogomu, Arpana Wadhwani, Ke Guo, Mina Ma, Victoria Barbeau, Bei Pan, Leenah Abdelrazeq, Zijun Li, Amjad Alghamyan, Liping Guo, Fatima Jahel, Junjie Ren, Mohamad Tarek Madani, Sarah Allam, Tarannum Hussain, Minyan Yang, Waleed Kojan, Xiuxia Li, Kehu Yang, Vivian Welch   +22 more
doaj   +1 more source

Frameworks for assessing digital health technologies: a scoping review. [PDF]

Int J Technol Assess Health Care
Rödiger H, Wittich LFM, Jeindl R, Hidaka Y, Bowie D, Rejón-Parrilla JC, Garrett Z, Busse R, Henschke C.   +8 more
europepmc   +1 more source

Development of information technology-based functional behavior assessment

The Proceedings of the Annual Convention of the Japanese Psychological Association, 2019
Tetsuya Yamamoto, Junichiro Yoshimoto
openaire   +2 more sources

EVALUATION OF TECHNOLOGY-BASED NEUROPSYCHOLOGICAL ASSESSMENTS IN OLDER ADULTS [PDF]

Innovation in Aging, 2018
A Steinert, A Latendorf, T Salminen, U Müller-Werdan   +3 more
openaire   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Health technology assessment in Eastern Europe and Central Asia: an updated SWOT analysis. [PDF]

Int J Technol Assess Health Care
Sucu R, Migliore A, Vicari N, Koç EM, Almadiyeva A.   +4 more
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Promoting the Dissemination of 3D Printing Technology in Reconstructing Critical-Sized Defects of Long Bone and Vertebral Body Through a "Six-in-One" Targeted Teaching Method. [PDF]

Adv Med Educ Pract
Liu B, Wang B, Wang Z, Li Y, Tian Y.
europepmc   +1 more source