Results 81 to 90 of about 4,155,604 (307)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

EdPuzzle: Technology-based Assessment in Mathematics Education

Journal of Advances in Mathematics and Computer Science
Aims: This study examines the effectiveness of EdPuzzle as a technology-based assessment tool in mathematics education, specifically in enhancing students’ comprehension of dividing rational expressions through interactive video lessons. Study Design: A quasi-experimental research design was employed, comparing pre-test and post-test results to assess
Rochelle Cigario, MARTIN NOBIS, Jr., Mike Lorden Adora, Cherry I. Balanquit   +3 more
openaire   +1 more source

Evidence-based indications for the planning of PET or PET/CT capacities are needed [PDF]

, 2019
Purpose To identify evidence-based indications for PET/PET–CT scans in support of facilities planning and to describe a pilot project in which this information was applied for an investment decision in an Austrian region.
Busse, Reinhard, Ferch, Manfred, Fuchs, Sabine, Grössmann, Nicole, Wild, Claudia   +4 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Building Information Modelling Incorporating Technology Based Assessment [PDF]

, 2011
Building Information Modelling (BIM) is currently being developed as a virtual learning tool for construction and surveying students in the Technological University Dublin. This advanced technology is also used to develop a technology based assessment practice for enhancing the learning environment of construction and surveying students.
Murphy, Maurice, Scott, Lloyd
openaire  

Advanced interdisciplinary technologies [PDF]

The following topics are presented in view graph form: (1) breakthrough trust (space research and technology assessment); (2) bionics (technology derivatives from biological systems); (3) biodynamics (modeling of human biomechanical performance based on ...
Anderson, John L.
core   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Teaching Physical Science Through Technology: Middle School VCU PHY 591 [PDF]

, 1999
Teaching Physical Science through Technology is a new 3-credit laboratory-and-lecture based course designed to serve as an introduction to the teaching of physical science concepts at the middle school level.
Hagan, D. B., Niculescu, V. A,
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

From Population Databases to Research and Informed Health Decisions and Policy

Frontiers in Public Health, 2017
BackgroundIn the era of big data, the medical community is inspired to maximize the utilization and processing of the rapidly expanding medical datasets for clinical-related and policy-driven research.
Yossy Machluf, Orna Tal, Orna Tal, Orna Tal, Amir Navon, Yoram Chaiter   +5 more
doaj   +1 more source