Results 21 to 30 of about 17,266,409 (358)

Smart technologies [PDF]

open access: yesInternet Policy Review, 2020
Speaking of ‘smart’ technologies we may avoid the mysticism of terms like ‘artificial intelligence’ (AI). To situate ‘smartness’ I nevertheless explore the origins of smart technologies in the research domains of AI and cybernetics. Based in postphenomenological philosophy of technology and embodied cognition rather than media studies and science and ...
openaire   +4 more sources

FoxO1 signaling in B cell malignancies and its therapeutic targeting

open access: yesFEBS Letters, EarlyView.
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac   +3 more
wiley   +1 more source

Informatics Education 2020 [PDF]

open access: yes, 2019
PIT-UN writes about Good Systems and the Conference on Undergraduate Informatics Education on March 3-4, 2020.Office of the VP for ...
Technology University Network, The Public Interest
core   +1 more source

The immunological interface: dendritic cells as key regulators in metabolic dysfunction‐associated steatotic liver disease

open access: yesFEBS Letters, EarlyView.
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi   +3 more
wiley   +1 more source

Dandelion Program 3 Year Report (Extended) [PDF]

open access: yes, 2018
The Dandelion Program is an initiative to build Information Technology, life, and executive functioning skills to help establish IT careers for people on the autism spectrum.
DXC Technology
core   +1 more source

Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells

open access: yesFEBS Letters, EarlyView.
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga   +6 more
wiley   +1 more source

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

Dandelion Program Generic Project Management Plan [PDF]

open access: yes, 2016
[Excerpt] There are significant benefits to clients in establishing an arrangement with Hewlett Packard Enterprise (HPE)/ Specialist People to access and acquire critical, skilled ICT resources by harnessing the talents and developing the skills of a ...
DXC Technology
core   +1 more source

Refining the NaV1.7 pharmacophore of a class of venom‐derived peptide inhibitors via a combination of in silico screening and rational engineering

open access: yesFEBS Letters, EarlyView.
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma   +8 more
wiley   +1 more source

How to Work Effectively with Colleagues on the Autism Spectrum [PDF]

open access: yes, 2018
MD_8024a_18_Dandelion_Program_autistic_colleagues_flyer_v3.pdf: 91 downloads, before Oct.
DXC Technology
core   +1 more source

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