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Speaking of ‘smart’ technologies we may avoid the mysticism of terms like ‘artificial intelligence’ (AI). To situate ‘smartness’ I nevertheless explore the origins of smart technologies in the research domains of AI and cybernetics. Based in postphenomenological philosophy of technology and embodied cognition rather than media studies and science and ...
openaire +4 more sources
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Informatics Education 2020 [PDF]
PIT-UN writes about Good Systems and the Conference on Undergraduate Informatics Education on March 3-4, 2020.Office of the VP for ...
Technology University Network, The Public Interest
core +1 more source
Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi+3 more
wiley +1 more source
Dandelion Program 3 Year Report (Extended) [PDF]
The Dandelion Program is an initiative to build Information Technology, life, and executive functioning skills to help establish IT careers for people on the autism spectrum.
DXC Technology
core +1 more source
Taurine promotes glucagon‐like peptide‐1 secretion in enteroendocrine L cells
Taurine, a sulfur‐containing amino acid, is likely taken up by enteroendocrine L cells via the taurine transporter. This process increases the levels of cytosolic ATP. The increase in intracellular Ca2+ concentrations and glucagon‐like peptide‐1 secretion through membrane depolarization is caused by the closure of ATP‐sensitive potassium channels ...
Yuri Osuga+6 more
wiley +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze+3 more
wiley +1 more source
Dandelion Program Generic Project Management Plan [PDF]
[Excerpt] There are significant benefits to clients in establishing an arrangement with Hewlett Packard Enterprise (HPE)/ Specialist People to access and acquire critical, skilled ICT resources by harnessing the talents and developing the skills of a ...
DXC Technology
core +1 more source
Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma+8 more
wiley +1 more source
How to Work Effectively with Colleagues on the Autism Spectrum [PDF]
MD_8024a_18_Dandelion_Program_autistic_colleagues_flyer_v3.pdf: 91 downloads, before Oct.
DXC Technology
core +1 more source