Results 41 to 50 of about 25,551,850 (384)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Healthcare technology and technology assessment [PDF]

open access: yesEuropean Spine Journal, 2007
New technology is one of the primary drivers for increased healthcare costs in the United States. Both physician and industry play important roles in the development, adoption, utilization and choice of new technologies. The Federal Drug Administration regulates new drugs and new medical devices, but healthcare technology assessment remains limited ...
James H, Herndon   +3 more
openaire   +3 more sources

DXC Dandelion Program: 2017 in Review [PDF]

open access: yes, 2018
[Excerpt] The Dandelion Program is an initiative to build valuable Information Technology, life, and executive functioning skills to help establish careers for people on the autism spectrum. The implementation and assessment of Dandelion pods (or ‘groups’
DXC Technology
core   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

Clay calcination technology: state-of-the-art review by the RILEM TC 282-CCL [PDF]

open access: hybrid, 2021
Theodore Hanein   +19 more
openalex   +1 more source

Dandelion Program Generic Project Management Plan [PDF]

open access: yes, 2016
[Excerpt] There are significant benefits to clients in establishing an arrangement with Hewlett Packard Enterprise (HPE)/ Specialist People to access and acquire critical, skilled ICT resources by harnessing the talents and developing the skills of a ...
DXC Technology
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Active learning narrows achievement gaps for underrepresented students in undergraduate science, technology, engineering, and math [PDF]

open access: hybrid, 2020
Elli J. Theobald   +32 more
openalex   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Microbial‑induced carbonate precipitation (MICP) technology: a review on the fundamentals and engineering applications [PDF]

open access: bronze, 2023
Kuan Zhang   +6 more
openalex   +1 more source

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