Results 41 to 50 of about 21,908,970 (349)

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Shaping Agility through Digital Options: Reconceptualizing the Role of Information Technology in Contemporary Firms

open access: yesMIS Q., 2003
Agility is vital to the innovation and competitive performance of firms in contemporary business environments. Firms are increasingly relying on information technologies, including process, knowledge, and communication technologies, to enhance their ...
V. Sambamurthy, A. Bharadwaj, V. Grover
semanticscholar   +1 more source

DXC Dandelion Program: 2017 in Review [PDF]

open access: yes, 2018
[Excerpt] The Dandelion Program is an initiative to build valuable Information Technology, life, and executive functioning skills to help establish careers for people on the autism spectrum. The implementation and assessment of Dandelion pods (or ‘groups’
DXC Technology
core   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Suspension Bridge Master Li: Professor Guohao Li [PDF]

open access: yes预应力技术, 2023
“Prestress Technology” Editorial Office
doaj   +1 more source

Architectural Technology and Technological Planning

open access: yesTechne, 2011
At least three fundamental aspects of the many singular technological approaches to architectural planning are currently evolving significantly and are ripe for potential development. The first relates to enhanced opportunities for defining the ex-ante characteristics and performance of building products and components, but particularly concerns ...
openaire   +3 more sources

Dandelion Program Generic Project Management Plan [PDF]

open access: yes, 2016
[Excerpt] There are significant benefits to clients in establishing an arrangement with Hewlett Packard Enterprise (HPE)/ Specialist People to access and acquire critical, skilled ICT resources by harnessing the talents and developing the skills of a ...
DXC Technology
core   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy