Results 51 to 60 of about 25,551,850 (384)

Organisation Change Plan: Getting Started [PDF]

open access: yes, 2019
[Excerpt] The vision of the program is the establishment of a capability within the organisation to attract, recruit, on-board and sustain talent from people on the autism spectrum. Why is this important? As we know we are in a war for talent to fuel our
DXC Technology
core   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Blockchain Technology for Intelligent Transportation Systems: A Systematic Literature Review [PDF]

open access: gold, 2022
Rateb Jabbar   +6 more
openalex   +1 more source

DXC Dandelion Program Objectives and Key Concepts [PDF]

open access: yes, 2019
The Dandelion Program provides people on the autism spectrum with the support, technical training and work experience needed to begin careers in ...
DXC Technology
core   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

DXC Dandelion Program: 2018 in Review [PDF]

open access: yes, 2018
[Excerpt] 2018 was another very successful year for the DXC Dandelion Program. DXC established a number of new, critical partnerships that continue to propel autism at work programs to the forefront of workplace inclusion.
DXC Technology
core   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Caltech and aeronautics: a presentation by the California Institute of Technology [PDF]

open access: yes, 1958
The outstanding accomplishment of Caltech in the field of aeronautics is not that it has taught, but that it has always had something new to teach. When most aircraft were glued together from bamboo, balsawood, and canvas, Caltech was teaching the next ...
California, Institute of Technology
core  

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

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