Results 71 to 80 of about 25,551,850 (384)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Older Adults Perceptions of Technology and Barriers to Interacting with Tablet Computers: A Focus Group Study [PDF]
, 2017 Eleftheria Vaportzis +2 more
openalex +1 more source
Learning First, Technology Second: Enhancing Missionary Training Through Technology [PDF]
, 2010 This article describes how the missions agency EFCA ReachGlobal uses the open source online learning platform Moodle to train missionaries and to fulfill its goal to become a learning organization.
Manges, Ernest, Morgenstern, Mark
core +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
, 2008 Technology games are parts of ways of life. The rules of technology games are the customary restrained practices people engage in, in consort with artefacts.
Monk, John
core