Results 51 to 60 of about 210,607 (311)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Affective Technology Acceptance Model: Extending Technology Acceptance Model with Positive and Negative Affect

, 2017
Research works on TAM, TAM2, TAM3 and UTAUT has always focused on cognitive aspect of technology acceptance in the past two decades. Acceptance of technologies such as eCommerce, Mobile and ERP that considered emotion and affect are still less. This creates a gap in the technology acceptance research, which consider the role of affect into technology ...
Lee, Angela Siew-Hoong, Thi, Lip Sam, Lin, Mei-Hua   +2 more
openaire   +4 more sources

Teori Dasar Technology Acceptance Model

, 2022
Buku ini adalah pengantar yang lengkap dan komprehensif untuk Technology Acceptance Model (TAM). Dalam buku ini, pembaca akan mempelajari konsep dasar dari TAM, termasuk komponen-komponennya, faktor-faktor yang mempengaruhi, dan cara mengimplementasikannya dalam lingkungan organisasi.
openaire   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Penggunaan e-learning dengan Technology Acceptance Model (TAM)

Jurnal Inovasi Teknologi Pendidikan, 2019
Kemajuan dalam teknologi informasi memberi kesempatan pada institusi pendidikan untuk mengadopsi teknologi untuk meningkatkan efisiensi pembelajaran.
Riski Nurida Rahmawati, I Made Narsa
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Acceptance of virtual reality-based hadith learning model with technology acceptance model (TAM) approach

JPPI (Jurnal Penelitian Pendidikan Indonesia)
The use of Virtual Reality (VR) technology in education is growing rapidly, including in the context of Islamic learning. This study aims to examine the acceptance of the VR-based Hadith learning model among students of the Islamic Religious Education ...
Muhammad Luthfi Hamzah, Ansharullah Ansharullah, Zetri Rahmat, M. Fahli Zatrahadi, Astri Ayu Purwati   +4 more
doaj   +1 more source

Digital entrepreneurial acceptance: an examination of technology acceptance model and do-it-yourself behavior

Journal of Innovation and Entrepreneurship, 2023
The study extended the existing literature on digital entrepreneurship, do-it-yourself and technology acceptance models with the help of empirical data.
Muhammad Ilyas, Arif ud din, Muhammad Haleem, Irshad Ahmad   +3 more
doaj   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

Molecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou, Zhen Wang, Fei Yang, Xiao Han, Lei Li, Huadong Liu   +5 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source