Results 51 to 60 of about 217,296 (257)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

A technology acceptance model of satellite-based hydrometeorological hazards early warning system in Indonesia: an-extended technology acceptance model

Cogent Business & Management
Purpose This study aims to develop and test a technology acceptance model for a satellite-based hydrometeorology early warning system in Indonesia.Design/methodology/approach The model was developed by extending TAM, through the inclusion of three ...
Igif Gimin Prihanto, Hendy Gunawan, Budhi Riyanto, Wiji Prasetio, Sik Sumaedi, Tri Rakhmawati, Nidya Judhi Astrini, Mahmudi   +7 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Penggunaan e-learning dengan Technology Acceptance Model (TAM)

Jurnal Inovasi Teknologi Pendidikan, 2019
Kemajuan dalam teknologi informasi memberi kesempatan pada institusi pendidikan untuk mengadopsi teknologi untuk meningkatkan efisiensi pembelajaran.
Riski Nurida Rahmawati, I Made Narsa
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Acceptance of virtual reality-based hadith learning model with technology acceptance model (TAM) approach

JPPI (Jurnal Penelitian Pendidikan Indonesia)
The use of Virtual Reality (VR) technology in education is growing rapidly, including in the context of Islamic learning. This study aims to examine the acceptance of the VR-based Hadith learning model among students of the Islamic Religious Education ...
Muhammad Luthfi Hamzah, Ansharullah Ansharullah, Zetri Rahmat, M. Fahli Zatrahadi, Astri Ayu Purwati   +4 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Analysis of Corporate Acceptance of Hydrogen Energy Technology Based on the Extended Technology Acceptance Model

Energies
Hydrogen holds an important strategic position in the energy systems of many countries. Many studies have analyzed the acceptance of hydrogen energy technology from the public’s perspective, but few have examined it from the corporate perspective.
Jianchao Hou, Han Wang
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source