Results 51 to 60 of about 21,474,219 (234)

Validation of Serious Games Attributes Using the Technology Acceptance Model [PDF]

, 2010
The paper introduces a conceptual model for the design of serious games and uses the Technology Acceptance Model (TAM) for its validation. A specially developed game introduced international students to public transport in Southampton.
Richard Crowder, Lester Gilbert, Yusoff, Amri, Gilbert, Lester, Crowder, Richard, Amri Yusoff   +5 more
core   +2 more sources

Artificial-intelligence-driven governance: addressing emerging risks with a comprehensive risk-prevention-centred model for public health crisis management

Health Research Policy and Systems
Background In response to the coronavirus disease 2019 (COVID-19) pandemic, an emerging public health crisis with global impact, various artificial intelligence (AI)-enabled devices for pandemic-prevention emerged, highlighting the urgent need to ...
Ching-Hung Lee, Zhichao Wang, Dianni Wang, Shupeng Lyu, Chun-Hsien Chen   +4 more
doaj   +1 more source

Genetic Ablation and Multi‐Omics Profiling Reveal CEP55 as a Key Driver of Tumorigenesis in Diverse Cancer Models

Advanced Science, EarlyView.
Genetic ablation of Cep55 in Pten‐deficient mouse models delays tumorigenesis. Integrated multi‐omics analyses (proteomics, phosphoproteomics, and spatial transcriptomics) reveal that CEP55 regulates oncogenic signaling (RAS/ERK, PI3K/AKT), integrin/FAK‐mediated adhesion, extracellular matrix (ECM) remodeling, and endocytosis.
Behnam Rashidieh, Yuanhao Yang, Amanda Louise Bain, Phillip Theron, Catharina Vosloo, Sahar Keshvari, Parinaz Ahangar, Brydie Bowden, Simon M. Tria, Ben B. Wang, Sandra Isenmann, Nicholas J. Westra van Holthe, Zherui Xiong, Hani Vu, Sowmya Sharma, Asmerom Sengal, J. Alejandro Lopez, John Finnie, Antonella Papa, Pascal H.G. Duijf, Quan Nguyen, Pirjo M. Apaja, Kum Kum Khanna   +22 more
wiley   +1 more source

BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer

Advanced Science, EarlyView.
BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu, Kangkang Liu, Keruo Wang, Heyang Guan, Jiaming Fan, Taipeng Li, Jiaru Hao, Zeyuan Wang, Yongchao Yan, Jiatong Chen, Yuan Ma, Yang Yang, Yuanjie Niu   +12 more
wiley   +1 more source

Use of ICT/WEB in Higher Education in Croatia: The Case of Economics and Management Studies [PDF]

International Journal of Management, Knowledge and Learning, 2017
The paper presents results of research on the acceptance and use of ICT and advanced web technology among teachers in the higher education process of Economics and Management in Croatia.
Josip Mesaric, Anita Prelas Kovacevic, Dario Šebalj   +2 more
doaj  

TECTAM, A modified technology acceptance model to assess E-commerce technologies adoption by Thai SME [PDF]

, 2007
In 2002, the Thai government has endorsed an information technology policy framework entitled Thailand Vision towards a Knowledge-Based Economy (IT 2010).
Depickere, A., Arnold A. Depickere, Fung, C.C., Chun Che Fung, Chooprayoon, V., Vasin Chooprayoon   +5 more
core   +1 more source

Redirecting Monocyte Differentiation With Engineered Extracellular Vesicles for Glioma Immunotherapy

Advanced Science, EarlyView.
A dual‐targeting engineered extracellular vesicles (M1‐CS‐EVs) platform is developed to redirect monocytes differentiation into anti‐tumor macrophages for glioma immunotherapy. This nanoplatform combines CAR‐mediated tumor recognition with localized CD47 blockade, leading to synergistic immune activation and potent suppression of tumor progression in ...
Yuanwei Pan, Xuan Liu, Qian‐Fang Meng, Lei Cao, Rongrong Li, Yangtao Xu, Jing Zhang, Chenchen Zhao, Lang Rao, Chen Yu   +9 more
wiley   +1 more source

Kajian Online Sistem Informasi BRI (BRINETS): Pendekatan Technology Acceptance Model (TAM)

Jurnal Akuntansi Multiparadigma, 2011
Study of BRI Online Information System (BRINETS): Technology Acceptance Model (TAM) Approach. The purpose of this research is to analyze factors that effecting acceptance and actual use of BRI technology information system (BRINETS) using TAM ...
Wahyu Meiranto
doaj  

Magneto‐NIR‐II‐Programmed Cascade Nanozymes Unlocking Blood–Brain Barrier Translocation and Autophagic Resistance in Glioblastoma

Advanced Science, EarlyView.
Magneto‐NIR‐II‐programmed NFSH nanozymes integrate magnetic blood–brain barrier (BBB) translocation, CD44 targeting, multimodal imaging, and cascade catalytic therapy for glioblastoma. Alternating magnetic fields and NIR‐II irradiation amplify ferroptosis, release H2S, suppress autophagic and mitophagic repair, and reshape the immune microenvironment ...
Ruocan Liu, Yundi Wu, Shuai Zhang, Hongjuan Zhao, Jiping Zheng, Shiyang Shao, Jianqiang Chen, Xilong Wu   +7 more
wiley   +1 more source

Exploring Technology Acceptance Models: A Systematic Review of Health Application Adoption in Asian Countries

Jurnal Manajemen dan Pelayanan Farmasi
Background: Health applications are a crucial technological advancement in healthcare, enhancing service quality and access to essential information. Despite this, challenges in implementation and user adaptation remain.
Ferina Septiani Damanik, Anna Wahyuni Widayanti, Chairun Wiedyaningsih   +2 more
doaj   +1 more source