Results 101 to 110 of about 7,254,348 (387)

Internet addiction and loneliness among children and adolescents in the education setting: an empirical pilot study [PDF]

, 2014
Research into various behavioural addictions has shown that such behaviour can negatively impact psychological wellbeing. One behavioural addiction that has been increasingly studied empirically is that of Internet Addiction (IA).
Griffiths, MD, Patrão, IM, Pontes, HM
core  

Technology Addiction: How Social Network Sites Impact our Lives

Informing Sci. Int. J. an Emerg. Transdiscipl., 2017
(CC BY-NC 4.0) This article is licensed to you under a Creative Commons Attribution-NonCommercial 4.0 International License. When you copy and redistribute this paper in full or in part, you need to provide proper attribution to it to ensure that others ...
Natalie Gerhart
semanticscholar   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Presenting a Structural Model of Online Gaming Addiction based on Social Rejection and Cognitive Ability with the Mediating Role of Emotional Avoidance

روانشناسی و روانپزشکی شناخت
Introduction: The pathological use of computer games has become one of the most important concerns of mental health professionals in recent years. Objective: This study aimed to propose a structural model for online gaming addiction, based on social ...
Mohammad Rreza Asadi , Matineh Ebadi, Mohammad Ali Ghaseminejad, Amir Masoud Asadi   +3 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

A Mediational Evaluation of Smartphone Addiction Effect on Insomnia and Sleepiness in Adolescents and Young Adults

Türk Uyku Tıbbı Dergisi
Objective: Good sleep quality is an important factor for a healthy life. The aim of this study was to investigate the factors affecting insomnia and daytime sleepiness in adolescents and young adults.
Fatma Atun Ütük, Onur Yücel, Masoumeh Asadi, Mert Yücel, Dilara Yanık, Hakan Demirhindi, Burak Mete, Esra Doğan Mete   +7 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

THE IMPACT OF SMARTPHONE USAGE IN ADOLESCENTS 15-24 YEARS OLD IN JABODETABEK REGION

The Indonesian Journal of Public Health, 2020
Youth and technology in the millennial era are inseparable. The need for technology makes smartphones the main needs that cannot be separated from the daily lives of youth.
Loveria Sekarrini
doaj   +1 more source