Results 51 to 60 of about 58,053 (264)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Cyber Hygiene as an Effective Psychological Measure in the Prevention of Cyber Addictions
Психология и правоProblematic internet use and addiction have grown globally with increased digital access and device usage. Individuals are spending more time online, frequently developing non-adaptive habits and addiction symptoms.
S.S. Gulyamov, A.A. Rodionov
doaj +1 more source
Association Between Digital Addiction and Physical Activity in Korean Adults Across Age Groups: An Analysis of Community Health Survey Data [PDF]
Journal of Preventive Medicine and Public HealthObjectives: Extensive research has been conducted on digital addiction, particularly concerning internet, gaming, and smartphone use among adolescents and young adults.
Kyungsin Lee, Inmyung Song
doaj +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Digital Addictive Technologies and State Security
EUROPEAN RESEARCH STUDIES JOURNAL, 2021 Purpose: The study aimed to identify the phenomenon of dependence on available digital technology devices, which may pose a potential threat to state security and adversely affect the health of society. Design/Methodology/Approach: A literature analysis and own statistical research were used as a research method to identify the problem of dependence on
openaire +3 more sources
Neuropsychiatric Investigation, 2020 Objective: The research was conducted analytic cross-sectional with the aim of determining the relationship between technology addiction and attachment styles in adolescents.
Cihan KOCAİRİ +3 more
doaj +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
روانشناسی و روانپزشکی شناختIntroduction: The pathological use of computer games has become one of the most important concerns of mental health professionals in recent years. Objective: This study aimed to propose a structural model for online gaming addiction, based on social ...
Mohammad Rreza Asadi +3 more
doaj +1 more source