Results 131 to 140 of about 1,536,208 (306)

Inhibition of Classical and Alternative Complement Pathway by Ravulizumab and Eculizumab

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore the feasibility of classical (CH50) and alternative (AH50) complement pathway activity as potential biomarkers for treatment guidance and monitoring during therapy with ravulizumab in patients with generalized myasthenia gravis (gMG) and compare these to therapeutic drug monitoring under eculizumab.
Lea Gerischer   +14 more
wiley   +1 more source

Machine Replacement, Technology Adoption and Convergence [PDF]

open access: yes
In this paper, we introduce adoption costs in a canonical vintage capital model. Adoption costs take the form of a direct loss in production during a fixed period of time. We explicitly characterize the optimal machine replacement policy as a function of
Boucekkine, Raouf, Martinez, Blanca
core  

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah   +7 more
wiley   +1 more source

Was the Wealth of Nations Determined in 1000 B.C.? [PDF]

open access: yes
We assemble a dataset on technology adoption in 1000 BC, 0 AD, and 1500 AD for the predecessors to today's nation states. We find that this very old history of technology adoption is surprisingly significant for today's national development outcomes. Our
Diego A. Comin   +2 more
core   +3 more sources

Knowledge, Technology Adoption and Financial Innovation [PDF]

open access: yes
Why are new financial instruments created? This paper proposes the view that financial development arises as a response to the contractual needs of emerging technologies.
Ana Fernandes
core  

Barriers to the adoption of health information technology [PDF]

open access: yes, 2011
Information Technology (IT) is successfully applied in a diverse range of fields. Though, the field of Medical Informatics is more than three decades old, it shows a very slow progress compared to many other fields in which the application of IT is ...
Nugawela, Saliya, Sahama, Tony
core   +1 more source

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein   +7 more
wiley   +1 more source

THE IMPACTS OF DAIRY CATTLE OWNERSHIP ON THE NUTRITIONAL STATUS OF PRE-SCHOOL CHILDREN IN COASTAL KENYA [PDF]

open access: yes
Anthropometric measurements for children and household characteristics were collected form 198 households in coastal Kenya to examine the impacts of dairy technology adoption on nutritional status.
Nicholson, Charles F.   +1 more
core   +1 more source

Olink Proteomics Analysis Reveals Heterogeneous Responses to FcRn Blockade in Anti‐AChR Antibody‐Positive Myasthenia Gravis: FGF‐19 as a Novel Biomarker

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to systematically observe the clinical manifestations, immune cell subsets, and dynamic changes in serological indicators in patients with myasthenia gravis (MG) before and after efgartigimod (EFG) treatment. Methods We analyzed the baseline data, laboratory parameters, and lymphocyte subset proportions in MG ...
Tiancheng Luo   +9 more
wiley   +1 more source

ADOPTION OF PRECISION AGRICULTURE TECHNOLOGY IN MISSISSIPPI [PDF]

open access: yes
Precision application technology has been an important topic in agriculture in recent years. This technology has the promise to improve farm management through improved information and control over in-field variability of soil characteristics and ...
Hite, Diane, Hudson, Darren
core   +1 more source

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