Results 91 to 100 of about 5,556,995 (307)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Annotated bibliography of Software Engineering Laboratory literature [PDF]

open access: yes
An annotated bibliography of technical papers, documents, and memorandums produced by or related to the Software Engineering Laboratory is given. More than 100 publications are summarized.
Morusiewicz, Linda, Valett, Jon D.
core   +4 more sources

油脂体的提取方法及其在食品中应用的研究进展Research progress on extraction methods and application in food of oleosomes

open access: yesZhongguo youzhi
旨在为油脂体的开发利用提供参考,综述了油脂体的结构与组成及提取方法,并介绍了油脂体在食品中的应用现状。油脂体以三酰甘油酯为核心,外层由磷脂-蛋白质膜覆盖,其主要由中性脂质、蛋白质和磷脂组成,此外还含有一些次要生物活性成分。油脂体的提取方法有水剂法、双螺杆压榨法和水酶法,可依据实际情况选择合适的提取方法。油脂体的特定结构以及生物活性成分使其作为天然预乳化水包油乳液具有良好的稳定性和乳化性能,在制备仿乳制品、可食用膜、乳液-凝胶以及作为脂肪替代品和生物活性物质运输载体等方面具有广阔的应用前景 ...
张亚靖1,陈复生1,王颖颖1,刘晨1,郑乾坤1,殷丽君2 (1.College of Food Science and Engineering, Henan University of Technology, Zhengzhou 450001, China; 2.School of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China)
doaj   +1 more source

Technology development in the country with the revision of engineering courses curriculum

open access: yesآموزش مهندسی ایران, 2016
Attention to innovation and technology are important factors in increasing a countny,s economic growth and competitiveness. There is no doubt that science and technology are the most basic elements of economic development, and successful countries are ...
firooz bakhtiari nejad , Nahid Sheikhan
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Pengembangan Modul Matematika dengan Pendekatan Science, Technology, Engineering, And Mathematics (STEM) pada Materi Segiempat

open access: yesDesimal, 2018
This study aims to determine the feasibility of mathematical modules with STEM approach and the response of learners and teachers to the attractiveness of the module.
Taza Nur Utami   +2 more
doaj   +1 more source

Creative Cognition in Engineering and Technology

open access: yes, 2022
Why do engineers need to use creative cognition? What purpose does it serve? How do engineers utilize creative cognition to achieve their desired ends? Do engineers, in fact, think about creativity differently from other disciplines?
openaire   +2 more sources

Editorial: Highlights in sports science, technology and engineering 2021/22. [PDF]

open access: yesFront Sports Act Living, 2022
Düking P   +4 more
europepmc   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Science, technology, engineering and mathematics: Australia’s future [PDF]

open access: yes
Presents recommendations for Australia to take a strategic approach to science and its related fields, focusing on: building competitiveness, supporting high quality education and training, maximising research potential and strengthening international ...

core  

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