Results 101 to 110 of about 5,556,995 (307)

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Aircraft Interior Design And Satisfaction For Different Activities; A New Approach Toward Understanding Passenger Experience

open access: yesInternational Journal of Aviation, Aeronautics, and Aerospace, 2019
Among airlines and aircraft manufacturers there is much attention for passenger experience. However, there is not much literature on how the activities of passengers can be supported by the aircraft interior. The current study focuses on the need finding
Golnoosh Torkashvand   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Attitudes of Engineering and Technology Teachers Towards the Use of Humanoid Robots in Education

open access: yesInternational Journal of Management, Knowledge and Learning
Purpose: The aim of the study was to investigate the attitudes of teachers of technical and engineering subjects towards the use of humanoid robots in the learning process.
Andrej Flogie   +2 more
doaj   +1 more source

Deployable platform systems development [PDF]

open access: yes, 1982
The long range objective is to achieve technology readiness for one or more deployable platform systems by 1986.
Jewell, R. E.
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Electrical/electronics working group summary [PDF]

open access: yes, 1984
The electrical/electronics, technology area was considered. It was found that there are no foreseeable circuit or component problems to hinder the implementation of the flywheel energy storage concept.
Schoenfeld, A. D.
core   +1 more source

On site challenges for the construction of 16-storey condominium: as observed by a young civil engineering technologist [PDF]

open access: yes, 2020
The difference between an engineer and an engineering technologist is that, an engineer would mainly focus and produce structural designs based on engineering calculations, while the job of an engineering technologist is to execute the design in the real
Chan, C. M.   +2 more
core  

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