Results 111 to 120 of about 4,522,828 (308)

Opportunities and exaggerations in the permeated and cybernetic scientific-technological world: an interdisciplinary reflection

Eikasía
This article critically examines the phenomenon of technological exaggeration (technology hype) within a scientific-technological and cyber-mediated society, focusing on how excessive expectations and promises shape economic, corporate, and scientific ...
Nicanor Ursua
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

When Intuition Meets the Algorithm: Medico-Legal Implications of Artificial Intelligence-Driven Decision-Making in Orthopedics

Bioengineering
Orthopedic surgery is undergoing a transformation driven by artificial intelligence (AI), which is reshaping clinico-surgical decision-making. While the operative strategy and professional responsibility traditionally relied on the surgeon’s intuition ...
Giuseppe Basile, Vittorio Bolcato, Giulia Bambagiotti, Luca Bianco Prevot, Livio Pietro Tronconi   +4 more
doaj   +1 more source

Preface : CAA 2010: Computer assisted assessment: supporting student learning [PDF]

, 2011
The Preface for the first special issue for the International Journal of e-Assessment highlights the role of the assessment for learning agenda. It also points to papers within the special issue which relate to: (a) Overcoming the barriers to supporting
Warburton, Bill, Whitelock, Denise
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Technology Assessment [PDF]

Academic Radiology, 1995
  +5 more sources

Was wirkt hat recht: Zur Konjunktur und Kritik des Wirkungsbegriffs und Schlussfolgerungen für die Technikfolgenabschätzung

TATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis
This research article develops a reflexive conception of ‘impact’ in technology assessment (TA). Impact is conceived as a relational and processual attribution that is co-produced by indicators and evaluation practices. Building on philosophical debates
Franziska Sörgel
doaj   +1 more source

Remote Diabetic Foot Temperature Monitoring for Early Detection of Diabetic Foot Ulcers: A Cost-Effectiveness Analysis

ClinicoEconomics and Outcomes Research, 2021
Elizabeth Brooks,1 Megan Burns,1 Ran Ma,2 Henk Jan Scholten,2 Shawn Becker3 1TTi Health Research and Economics, Westminster, MD, USA; 2Siren Care, Inc, San Francisco, CA, USA; 3Silvercat Advisors, LLC, Burlingame, CA, USACorrespondence: Megan BurnsTTi ...
Brooks E, Burns M, Ma R, Scholten HJ, Becker S   +4 more
doaj  

Comments on TEC trends [PDF]

A technology assessment of thermionic energy conversion research and technology is ...
Morris, J. F.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source