Results 121 to 130 of about 1,567,434 (318)

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

The K to 12 Senior High School Technica-Vocational Livelihood Track is Not at All Ready for Implementation

JPAIR Institutional Research Journal, 2015
The K to 12 program in the Philippines was enacted into law on May 15, 2013, through Republic Act 10533, otherwise known as the Enhanced Basic Education Act of 2013.
Florencio R. Caballero, Ruth G. Cabahug
doaj   +1 more source

Health information science and technology education: An analysis of health informatics undergraduate and postgraduate programs in arab countries. [PDF]

Heliyon, 2023
Almehmadi FM.
europepmc   +1 more source

Future Prospects of Technology Education [PDF]

peer reviewedThe first three volumes of the CETE publication series took stock of the discipline of technology education, its fields of research and its impact for personality development.

core  

Technology Education for Sustainable Futures

, 2006
The article develops the argument that Technology education has a particular and important role in achieving sustainable futures within different societies.
Pavlova, Margarita
core   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Learning Module Innovation Interactive for Counseling Guidance: Technology Integration in Increase Intelligence Emotional Student

Jurnal Evaluasi dan Pembelajaran
Emotional intelligence is an important component in learner development, especially in facing social and psychological challenges during adolescence.
Fera Yusnitarini, Rangga Firdaus
doaj   +1 more source

Lessons learned through crisis: the effect of Covid-19 on pre-service Technology Education teacher development. [PDF]

Int J Technol Des Educ, 2023
Kennedy T, Gill D.
europepmc   +1 more source

Creativity and Design in Technology & Engineering Education

, 2011
Creativity has been associated with the peak experiences in one’s life. Giving birth to new ideas, relationships, and objects usually requires effort, perseverance, and know-how.

core  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source