Results 71 to 80 of about 720,141 (268)

Editorial: PROTACs: Targeted therapies for cancer treatment

Frontiers in Cell and Developmental Biology, 2023
Sobia Tabassum
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Body donor reperfusion and re-ventilation in medical training: an Italian study testing SimLife®

Frontiers in Medicine
BackgroundMedical simulations have emerged as a valuable tool in anatomical-medical training, allowing healthcare professionals to gain hands-on experience in a controlled and safe environment.
Irene Neri, Giulio Vara, Antonietta Fazio, Maria Vittoria Marvi, Foteini-Dionysia Koufi, Elisa Boschetti, Simone Lodi, Giulia Adalgisa Mariani, Marilisa Quaranta, Anna Maria Billi, Alessandra Ruggeri, Carlo Barausse, Cyril Brèque, Annalisa Plava, Veronica Moretti, Lucia Manzoli, Stefano Ratti   +16 more
doaj   +1 more source

Technological Innovation, Entrepreneurship, and Development [PDF]

, 2011
Industrialization has long been seen as the answer to underdevelopment and poverty. First this led countries to follow protectionist import substitution policies but as these failed developing countries have opened up to trade and FDI and tried to follow strategies of export driven industrialization.
Audretsch, David B., Sanders, Mark
openaire   +5 more sources

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Science and Technology Backyard: A novel approach to empower smallholder farmers for sustainable intensification of agriculture in China

Journal of Integrative Agriculture, 2019
Sustainable feeding of the growing population in China without ecological destabilization is a grand challenge. In this populous country where agriculture is dominated by smallholder farming, developing innovative technology and translating scientific ...
Xiao-qiang JIAO, Hong-yan ZHANG, Wen-qi MA, Chong WANG, Xiao-lin LI, Fu-suo ZHANG   +5 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Innovative Strategies And Innovative Technologies.

, 2018
In the course of the research: the definition of "innovation potential" is given; normative and legal acts regulating innovative activity are summarized; the tendency to decrease in activity of innovative activity in Ukraine is revealed; foreign experience and the role of innovative strategies in increasing the competitiveness of products, enterprises,
Svitlana Filyppova, Valentyna Saadzhan
openaire   +4 more sources