Results 111 to 120 of about 3,163,990 (308)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Appraising the integration of sustainable development into sectoral policies: The case of Turkish Science & Technology policies [PDF]
This paper presents the results of a study investigating how sustainable development can be integrated in Turkish science and technology policies.
Cédric Gossart, Erkan Erdil
core
Planar microfluidics - liquid handling without walls
, 2001 The miniaturization and integration of electronic circuitry has not only made the enormous increase in performance of semiconductor devices possible but also spawned a myriad of new products and applications ranging from a cellular phone to a personal ...
Adamson +34 more
core +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
能源环境保护Fiber-reinforced polymers (FRPs), composed of reinforcing fibers and resin matrices, exhibit outstanding characteristics such as low density, high strength, corrosion resistance, and superior mechanical performance.
Long JIAO +7 more
doaj +1 more source
Aeroelastic modeling for the FIT (Functional Integration Technology) team F/A-18 simulation [PDF]
As part of Langley Research Center's commitment to developing multidisciplinary integration methods to improve aerospace systems, the Functional Integration Technology (FIT) team was established to perform dynamics integration research using an existing ...
Wieseman, Carol D., Zeiler, Thomas A.
core +1 more source
InP nanocrystals on silicon for optoelectronic applications
, 2012 One of the solutions enabling performance progress, which can overcome the downsizing limit in silicon technology, is the integration of different functional optoelectronic devices within a single chip. Silicon with its indirect band gap has poor optical
Helm, Manfred +10 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Factors influencing in-service teachers' technology integration model: Innovative strategies for educational technology. [PDF]
PLoS One, 2023 Peng R, Abdul Razak R, Hajar Halili S.
europepmc +1 more source