Results 111 to 120 of about 3,418,997 (346)

Africa (COVID-19) Vaccine Technology Transfer: Where Are We? [PDF]

Life (Basel), 2023
Oladipo EK, Olufemi SE, Ojo TO, Adediran DA, Idowu AF, Idowu UA, Onyeaka H.   +6 more
europepmc   +1 more source

OAST space research and technology applications: Technology transfer successes [PDF]

The ultimate measure of success in the Space Research and Technology Program is the incorporation of a technology into an operational mission. Charts are presented that describe technology products which OAST has helped support that (1) have been used in
Reck, Gregory M.
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Design and Operating Performance of Mechanical Draft Dry Cooling Tower Pre-cooled with Wet Medium

Zhongguo dianli
In order to solve the problem of insufficient output of mechanical draft dry cooling tower which can’t meet the cooling demand in summer, a mechanical draft dry cooling tower with wet medium pre-cooling inlet air system is designed in this paper.
Mingwei WANG, Tiantian LIU, Qi GAO, Chunwei WANG, Jiyong SHEN, Shoufu LIU, Suoying HE   +6 more
doaj   +1 more source

The Greening of Technology Transfer: A Conference Summary [PDF]

, 1995
Dr. Hennessey briefly reports on an international conference that explored the relationship between patent and other intellectual property laws and those designed to protect the environment and maintain ...
Hennessey, William O.
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Intra-firm Technology Transfer and R&D in Foreign Affiliates: Substitutes or Complements? Evidence from Japanese Multinational Firms [PDF]

R&D in foreign affiliates and technology transferred from their parent firms are important potential drivers of productivity in host countries. In this paper we examine the simultaneous impact of local R&D and intra-firm international technology transfer
Belderbos, René, Ito, Banri, Wakasugi, Ryuhei   +2 more
core  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

Cryogenic transfer options for exploration missions [PDF]

The literature of in-space cryogenic transfer is reviewed in order to propose transportation concepts to support the Space Exploration Initiative (SEI). Forty-nine references are listed and key findings are synopsized.
Chato, David J.
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source