PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Evaluation of laboratory workers competency on loop mediated isothermal amplification (LAMP) technology for malaria diagnostics: a technology transfer assessment study (LAMP-TTA) during a multi-site clinical trial. [PDF]
Tegegne B, Kamaliddin C, Pillai DR.
europepmc +1 more source
Effects of incorporating public innovation intermediaries on technology transfer performance: evidence from patent licensing of Japan's Kohsetsushi. [PDF]
Fukugawa N.
europepmc +1 more source
Soil and landscape affecting technology transfer targeting subsistence farmers in central Tanzania
Nadja Reinhardt +8 more
openalex +1 more source
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Evaluation frameworks for technology transfer projects: Lessons from Japan's global growth of medical technologies initiatives in low- and middle-income countries. [PDF]
Yokobori Y +9 more
europepmc +1 more source
Fostering reproducibility, reusability, and technology transfer in health informatics. [PDF]
Hauschild AC +3 more
europepmc +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source

