Results 191 to 200 of about 10,992,361 (296)

Re-Engineering the Educational System: Technology Transfer from a Behavioral Perspective. [PDF]

Perspect Behav Sci
Twyman JS.
europepmc   +1 more source

Examining the trade-offs in clean energy provision: Focusing on the relationship between technology transfer, renewable energy, industrial growth, and carbon footprint reduction. [PDF]

Heliyon, 2023
Zhou Q, Wu J, Imran M, Nassani AA, Binsaeed RH, Zaman K.   +5 more
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Technology Transfer of O-(2-[18F] Fluoroethyl)-L-Tyrosine (IASOglio^®) Radiopharmaceutical. [PDF]

Pharmaceuticals (Basel)
Notaro A, Limpido S, Plougastel L, Zega A, Telleschi M, Quaglierini M, Danti A, Fiore A, Guiducci L, Poli M.   +9 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

How to promote university technology transfer? A configuration analysis based on technology, organization and environment framework. [PDF]

PLoS One
Wang X.
europepmc   +1 more source

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Proof-of-principle of a technology transfer of a dried blood virus neutralisation assay to a Gavi-eligible country. [PDF]

BMJ Glob Health
Obodai E, Terstappen J, Mensah JY, Versnel A, Antwi CN, Bont LJ, Cianci D, Delemarre EM, Odoom JK, van de Ven PM, Mazur NI.   +10 more
europepmc   +1 more source

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

FEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson, Anja H. Schiemann, Evelyn Sattlegger   +2 more
wiley   +1 more source

Evaluation frameworks for technology transfer projects: Lessons from Japan's global growth of medical technologies initiatives in low- and middle-income countries. [PDF]

GHM Open
Yokobori Y, Miyagi A, Nagai M, Shimizu E, Ito T, Miyazaki K, Fujii M, Nishioka T, Haruyama R, Egami Y.   +9 more
europepmc   +1 more source