Results 191 to 200 of about 3,418,997 (346)

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Technology Transfer of O-(2-[18F] Fluoroethyl)-L-Tyrosine (IASOglio^®) Radiopharmaceutical. [PDF]

Pharmaceuticals (Basel)
Notaro A, Limpido S, Plougastel L, Zega A, Telleschi M, Quaglierini M, Danti A, Fiore A, Guiducci L, Poli M.   +9 more
europepmc   +1 more source

What drives successful sustainable technology transfer in emerging open innovation ecosystems

Saša Petković, Jadranka Petrović, Vesna Bucevska, Marija Radosavljević, Elona Pojani   +4 more
openalex   +1 more source

Analyzing the Effectiveness of University Technology Transfer: Implications for Entrepreneurship Education [PDF]

We review and synthesize the burgeoning literature on institutions and agents engaged in the commercialization of university-based intellectual property.
Donald S. Siegel, Phillip H. Phan
core  

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Re-Engineering the Educational System: Technology Transfer from a Behavioral Perspective. [PDF]

Perspect Behav Sci
Twyman JS.
europepmc   +1 more source

Spatiotemporal characteristics and influencing factor analysis of universities' technology transfer level in China: The perspective of innovation ecosystems. [PDF]

PLoS One, 2022
Fang H, Wang J, Yang Q, Liu X, Cao L.
europepmc   +1 more source

IMPLEMENTATION OF TECHNOLOGIES FOR ANALYSIS AND VISUALIZATION OF DATA FROM THE PORT AND WATERWAY SECTOR OF MARANHÃO: AN INNOVATIVE APPROACH TO TECHNOLOGY TRANSFER [PDF]

Francisco Odencio Rodrigues de Oliveira Junior
openalex  

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

How to promote university technology transfer? A configuration analysis based on technology, organization and environment framework. [PDF]

PLoS One
Wang X.
europepmc   +1 more source