Results 41 to 50 of about 3,418,997 (346)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Hematopoietic (stem) cells—The elixir of life?

open access: yesFEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo   +4 more
wiley   +1 more source

Effects of yeast extract and methyl jasmonate on the enhancement of solasodine biosynthesis in cell cultures of Solanum hainanense Hance [PDF]

open access: yesJournal of BioScience and Biotechnology, 2014
In this work, the effects of the elicitors methyl jasmonate (MeJA) and yeast extract (YE) on the growth and solasodine production of Solanum hainanense cells were investigated. The results showed that various concentrations of MeJA (50-250 µM) and YE (1-4
NGUYEN HOANG LOC   +3 more
doaj  

Yield and carrying capacity of meadows in Albania [PDF]

open access: yesRatarstvo i Povrtarstvo, 2011
This study was carried out during 2003-2005 and included total meadow surface of 32,000 ha from seven regions throughout Albania (summer meadows of Shishtavec, Gramoz, Çajup, Lenie, Progonat, and winter meadows of Heremec-Delvine and Dukaj).
Hajno Luan, Tahiri Fiqiri
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Use of organic amendments for sustainable management of root rot disease of tomato (Solanum lycopersicum L.) caused by Sclerotium rolfsii

open access: yesScientific Reports
The utilization of organic amendments has been considered as the best nonchemical management strategy for controlling the soil borne pathogens and hence can act as a potential tool to manage different soil borne diseases of tomato.
Dipankar Mandal   +7 more
doaj   +1 more source

Challenges and care strategies associated with the admission to nursing homes in Germany: a scoping review

open access: yesBMC Nursing, 2023
Background The admission to a nursing home is a critical life-event for affected persons as well as their families. Admission related processes are lacking adequate participation of older people and their families. To improve transitions to nursing homes,
Stefanie Skudlik   +6 more
doaj   +1 more source

Does phosphogypsum application affect salts, nutrients, and trace elements displacement from saline soils?

open access: yesFrontiers in Environmental Science, 2022
Salinity and sodicity are the most agricultural challenges in arid and semi-arid regions. A pot experiment was undertaken, to evaluate the effect of Phosphogypsum (PG) and Gypsum (G), to remove salts, nutrients and trace elements in leached water from ...
M Barka Outbakat   +5 more
doaj   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

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