Results 61 to 70 of about 10,992,361 (296)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Advanced technology and knowledge transfer [PDF]
36th Annual Hawaii International Conference on System Sciences, 2003. Proceedings of the, 2003 This paper reports on a specific food and agribusiness industry project, employing new technological capabilities to better transfer expert knowledge. Knowledge transfer and technical support are key components of this project. VisIT, which stands for visualization of information tool, is a powerful organizational tool, which provides an Internet-based
Tandon, Geetanjali, Sonka, Steven T.
openaire +2 more sources
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Technology Transfer and Valuation Methods in Use by University Technology Transfer Offices
, 2023 Valuing research deliverables implies the assessment of knowledge, skills, and solutions that can create benefits for a wide scope of stakeholders, including researchers, research units, universities, businesses, and the larger society. Investing in early-stage technology or technology that is novel and has an inventive step can imply a high-risk ...
António Rocha +4 more
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Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
BMJ, 2000 Global health relies on biomedical scientists and public health workers to solve infectious disease and other health problems at a local level. Yet investigators in developing countries face tremendous obstacles; scientific isolation, insufficient technical training and research tools, a lack of up to date scientific information, and limited financial,
E, Harris, M, Tanner
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Technology Transfers for Climate Change [PDF]
SSRN Electronic Journal, 2012 This article considers the transfer of cost‐reducing technology in the context of contributions to climate protection. We analyze a two‐period public goods model where later contributions can be based on better information, but delaying the mitigation effort is costly because of irreversible damages.
May Elsayyad, Florian Morath
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Agricultural Extension in the Pluralistic Ecosystem in India
International Journal of Bio-Resource and Stress Management, 2017 Agricultural extension has played a pivotal role in the agricultural development in India. It is turning new leaf every day, adding new dimension to itself.
Jagriti Rohit +4 more
doaj
Journal of Agrometeorology, 2017 A study was undertaken at Regional Research and Technology Transfer Station, Chiplima, Sambalpur, Odisha on rice var. khandagiri during summer season of 2011, 2012 and 2013 in split plot design with three irrigation schedule (main plots) and three date ...
B.R. NAYAK +6 more
doaj +1 more source