Results 11 to 20 of about 50,499 (210)
Los autores quieren agradecer el apoyo de NEUROTEC – Red Temática de Investigación en Neurotecnologías para la Asistencia y la Rehabilitación (DPI2015-69098-REDT), financiada por Ministerio de Economía y Competitividad.
Barrios, Luis J. +5 more
openaire +5 more sources
Babel: crónica de la variación
A partir de recuperar la experiencia vital y cotidiana, mediada por el vínculo con las nuevas tecnologías, del personaje Babel, se reflexiona en torno a los cambios en la dinámica social en relación con la hipertrofia de la dimensión comunicacional.
Federico Juan Bauso Beltrán
doaj +1 more source
Lineamiento sobre tecnologías de comunicación para educación inclusiva en universidades públicas
En el marco de la tesis doctoral, se propuso un objetivo específico que buscó generar un lineamiento estratégico sobre tecnologías de la comunicación en la Universidad Nacional Abierta y a Distancia y Universidad Pedagógica Nacional, a fin de fortalecer ...
Sandra Acevedo Zapata
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Acute caffeine treatment protects the developing retina from ischemia‐induced cell death
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento +6 more
wiley +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
O texto discute a relação entre formação de professores e tecnologias digitais na escola. Procura compreender as representações, apropriações e práticas de professores da educação básica, analisando criticamente a formação docente para o uso das novas ...
Onilza Borges Martins +1 more
doaj +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source
Tecnologías y cuidados en residencias de mayores. Tensiones y conflictos éticos
El estudio de la interrelación cuidados‑tecnociencias constituye un campo novedoso y dinámico de la investigación social, como muestran los Proyectos (anonimizados) en que se inscriben los resultados aquí presentados.
Maria Teresa Martin Palomo +1 more
doaj +1 more source

