Results 21 to 30 of about 2,792 (202)

Indagando sobre el papel de la tecnología en el aula [PDF]

, 2014
En este trabajo abordamos la problemática de investigación sobre el papel de la tecnología en el aula, centrándonos en el profesor. Utilizaremos la complementariedad entre dos ideas socioculturales, orquestación instrumental y modelación de la ...
Gavilán-Izquierdo, José María
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

The Effectiveness of a Brief Intervention for Reducing Adolescent Alcohol Consumption

Revista Ciencias de la Salud, 2018
Introduction: Although alcohol consumption affects more than half of all adolescents, there are no known studies to assess the effectiveness of interventions to prevent or reduce consumption at a local level. The aim of this randomized clinical trial was
Karina Conde, Romina Antonela Brandariz, Aldana Lichtenberger, Mariana Cremonte   +3 more
doaj   +1 more source

Conocimiento del estudiantes y saber institucional en situaciones de aprendizaje con uso de software de geometría dinámica [PDF]

, 2016
El texto presenta elementos preliminares del proyecto de investigación sobre el conocimiento del estudiante y saber institucional en situaciones de aprendizaje con uso de software de geometría dinámica inscrito en la línea de investigación tecnologí
Díaz, Faberth
core  

Ceramic Tile Design: a Case Study of Collaborative New-Product Development in Fashion-Driven Chains [PDF]

, 2009
This paper studies ceramic tile design chains, as representative of those collaborative New-Product Development (NPD) processes where the presence of very different origins of designs and the fast changes of the market strongly condition the process.
Agost, Maria-Jesus, Company, Pedro, Romero Subirón, Fernando   +2 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Avances y desafíos de la formación investigativa en la carrera de Pedagogía de la Universidad Politécnica Salesiana de Ecuador [PDF]

, 2014
El presente ensayo es una aproximación inicial a la formación investigativa de la Carrera de Pedagogía de la Universidad Politécnica Salesiana de Ecuador (UPS) y fue elaborado como una exigencia del curso “Problemas sociales de la ciencia y la ...
Romero Ortega, Armando
core  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Geogebra: de artefacto a instrumento proceso de transformación [PDF]

, 2016
En la actualidad, todavía hay dificultades para integrar y articular la tecnología (en este caso el software libre de matemáticas dinámicas GeoGebra) sea posible. Una de ellas tiene que ver con resistencias y falta de voluntad del profesorado debido,
Ardila, Pablo, Córdoba, Francisco
core  

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon, Nathalie Picard, Valeria d'Andrea, Enchi Chang, Joseph Leffler, Eleonora Centofante, Matthew Taylor, Francesca Bardi, Francesca Cavicchiolo, Takao K. Hensch, Stefano Panzeri, Chinfei Chen, Michela Fagiolini   +12 more
wiley   +1 more source