Results 11 to 20 of about 726,968 (222)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

open access: yesFEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão   +3 more
wiley   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

open access: yesFEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro   +1 more
wiley   +1 more source

Revista E.T.C. Educação, tecnologia e cultura (arquivo 2 de 2)

open access: yes, 2016
Revista do Instituto Federal de Educação, Ciência e Tecnologia da ...
Educação, Tecnologia e Cultura, Revista E.T.C.
core   +3 more sources

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Revista E.T.C. Educação, tecnologia e cultura (arquivo 1 de 2)

open access: yes, 2016
Revista do Instituto Federal de Educação, Ciência e Tecnologia da ...
Educação, Tecnologia e Cultura, Revista E.T.C.
core   +3 more sources

Conheça o Instituto de Tecnologia Educativa [PDF]

open access: yes, 1984
DivulgaçãoPrograma dedicado a dar a conhecer o Instituto de Tecnologia Educativa - ITE e o trabalho desenvolvido.N/
Instituto de Tecnologia Educativa
core  

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis From ELSA‐Brasil

open access: yesArthritis Care &Research, EarlyView.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada   +7 more
wiley   +1 more source

Sistema de secado combinado para cerámica mediante tecnología microondas para el sector de la cerámica hasta formato 1200

open access: yesBoletín de la Sociedad Española de Cerámica y Vidrio, 2010
New team of passage by technology microwaves for dried laminar of materials of high absorption, and dried green porcelain format until 1200 mm and thicknesses until 25 mm.
TECNOLOGIA,SL, BULMA
doaj  

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