Results 21 to 30 of about 1,522,910 (330)

Tecnologia social: uma estratégia para o desenvolvimento [PDF]

, 2004
Esta publicação apresenta reflexões de diversos representantes de instituições governamentais, do terceiro setor, da sociedade civil e de universidades sobre o tema da Tecnologia ...
Antonio E. Lassance, Jr., Claiton José Mello, Eduardo José Siqueira Barbosa, Flávio Cruvinel Brandão, Henrique Tahan Novaes, Jacqueline Rutkowski, Jacques De Oliveira Pena, Juçara Santiago Pedreira, Ladislau Dowbor, Paul Singer, Renato Dagnino, Sidney Lianza, Silvio Caccia Bava, Sonia Maria Portella Kruppa   +13 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Finding efficient nonlinear functions by means of genetic programming [PDF]

, 2003
7th International Conference, KES 2003. Proceedings, Part I. Oxford, UK, September 3-5, 2003The design of highly nonlinear functions is relevant for a number of different applications, ranging from database hashing to message authentication.
Hernández, Julio C., Isasi, Pedro, Luque, Cristóbal   +2 more
core   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Sistema de secado combinado para cerámica mediante tecnología microondas para el sector de la cerámica hasta formato 1200

Boletín de la Sociedad Española de Cerámica y Vidrio, 2010
New team of passage by technology microwaves for dried laminar of materials of high absorption, and dried green porcelain format until 1200 mm and thicknesses until 25 mm.
TECNOLOGIA,SL, BULMA
doaj  

Day/night variations of myeloid and lymphoid cell subsets in the murine inguinal lymph node

FEBS Open Bio, EarlyView.
The circadian system is involved in the temporal regulation of the immune system. Our study reveals that two innate immune populations, NKT cells and neutrophils, predominate at the beginning of the day in healthy mice, highlighting how the time of day influences immune responses.
Paula M. Wagner, César G. Prucca, Lucia Boffelli, Virginia A. Piqueras, Silvia G. Correa, Mariana Maccioni, Mario E. Guido   +6 more
wiley   +1 more source

Tecnologias Disruptivas e Tecnologias Educativas

Revista Brasileira de Aprendizagem Aberta e a Distância
Já é consolidado e de senso comum que as Tecnologias Digitais de Informação, Comunicação e Expressão (TICE) e outras tecnologias disruptivas impactam irreversivelmente todas as modalidades de ensino. No âmbito da Educação Profissional e Tecnológica, a adoção de novos modos de formação em resposta a esses impactos torna-se uma necessidade premente ...
openaire   +2 more sources

Strengthening Resilience by thinking of Knowledge as a nutrient connecting the local person to global thinking: The case of Social Technology/Tecnologia Social [PDF]

, 2015
In this chapter, we describe the Knowledge as a Nutrient framework that emerged from these conversations. We describe how it relates to the Tecnologia Social policy approach to sustainability, developed in Brazil (Dagnino et al.
Bazely, Dawn R., Duailibi, M., Klenk, N., Perkins, Patricia E. (Ellie)   +3 more
core