Results 31 to 40 of about 3,674 (136)

6‐Month Clinical Evaluation of Reduced Dentin Etching Time Using Universal Adhesives in Noncarious Cervical Lesions: A Double‐Blind Randomized Clinical Trial

open access: yesJournal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objectives To evaluate the effect of reduced dentin etching time on the clinical performance of two universal adhesive systems in noncarious cervical lesions (NCCLs). Methods A total of 144 NCCLs restorations were randomly placed in 36 participants according to four experimental groups: SUP5 (Scotchbond Universal Plus adhesive [pH ≈2.5–2.7 ...
Mario Felipe Gutiérrez   +4 more
wiley   +1 more source

Physiological and Sleep Profiles in Insomnia, OSA and COMISA: A Comparative Study in Portugal and Spain

open access: yesJournal of Sleep Research, EarlyView.
ABSTRACT Insomnia and obstructive sleep apnea (OSA) are common sleep disorders that often co‐occur as comorbid insomnia and sleep apnea (COMISA), worsening health outcomes. This study characterized and compared the physiological and sleep profiles of insomnia, OSA and COMISA in population‐based datasets from Portugal (n = 147) and Spain (n = 264 ...
Margarida Carvalho   +9 more
wiley   +1 more source

Cannabinoid and adenosine A2A receptor crosstalk regulates postnatal and adult hippocampal neurogenesis

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 18, Page 5440-5457, September 2026.
Background and purpose Adult neurogenesis is a tightly regulated process affected by both cannabinoid receptors (CB1 and CB2) and adenosine 2A (A2A) receptors, both of which modulate neural progenitor cell activity. While emerging evidence suggests an interaction between these neuromodulatory systems, the extent and mechanism of their interplay in ...
Rui S. Rodrigues   +8 more
wiley   +1 more source

Systemic and Local Adiposity in the Bone Marrow Microenvironment Associated With Improved Prognosis in Hodgkin Lymphoma: Imaging and Molecular Analysis

open access: yesInternational Journal of Cancer, Volume 159, Issue 3, Page 782-796, 1 August 2026.
Schematic overview of systemic and bone marrow‐specific adiposity in Hodgkin Lymphoma (HL). Body Mass Index was associated with bone marrow (BM) involvement, relapse, and mortality (1). In contrast, increased yellow marrow density was associated with poorer prognosis (2).
Andreia Matos   +22 more
wiley   +1 more source

Rituximab Binding Endows CD20+ Extracellular Vesicles With NK Cell‐Activating Properties in B Cell Lymphoma

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 8, August 2026.
B cell lymphoma‐derived EVs are intrinsically neutral or suppressive with respect to NK cell activity (panel 1). In the context of rituximab treatment, NK cytotoxicity is enhanced by antibody‐dependent cell‐mediated cytotoxicity (panel 2). Herein we show that, in addition, rituximab recognition of EV‐associated CD20 generates immune complexes that ...
Adrián V. Otero   +19 more
wiley   +1 more source

Acesso à tecnologia biomédica: perspectiva bioética dos enfermeiros portugueses

open access: yesRevista Bioética, 2014
Atualmente, as sociedades industrializadas são caracterizadas pela diminuição da taxa de natalidade, envelhecimento populacional e aumento das doenças crônicas e degenerativas.
Ana Maria Pinto Saraiva
doaj  

Schedule‐dependent neuroprotection by pioglitazone in a novel model of α‐synucleinopathy in rats: Integrated behavioural and histological outcomes

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 15, Page 4227-4245, August 2026.
Background and Purpose α‐Synucleinopathies are neurodegenerative disorders characterized by the aggregation and propagation of misfolded α‐synuclein. In Parkinson's disease (PD), the most common α‐synucleinopathy, the progression of motor and nonmotor deficits, and dopaminergic neuron loss, are closely linked to the spreading of misfolded α‐synuclein ...
Alberto Santiago‐Balmaseda   +5 more
wiley   +1 more source

Mechanically Programmable DNA Hydrogel Microparticles for 3D Cellular Systems

open access: yesAdvanced Materials, Volume 38, Issue 37, 2 July 2026.
DNA hydrogel microparticles are designed to exhibit controllable viscoelasticity and stiffness across three orders of magnitude from 30Pa$30 \,\mathrm{Pa}$ to 6.5kPa$6.5 \,\mathrm{kPa}$. They are uptaken into fibroblast spheroids where they are actively remodeled by cellular forces depending on their mechanical properties.
Tobias Walther   +9 more
wiley   +1 more source

Prototipo de electrocardiógrafo bipolar para uso académico

open access: yesCiencia y Poder Aéreo, 2014
Para la preparación del personal médico en la adquisición, procesamiento, visualización y almacenamiento de señales cardíacas, la tecnología ofrece una serie de equipos y dispositivos de alta calidad y alto costo, además de ser ensamblados de forma ...
Leonardo Juan Ramírez López   +2 more
doaj   +1 more source

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