Results 171 to 180 of about 440,080 (310)

New Approach Methodologies (NAMs) in Alternative Methods: A Comparative Cytotoxicity Analysis of Nanostructured Hydroxyapatite in Adipose Stem Cells Spheroids

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Toxicological assessment is essential in NP approval for health and medical applications. Although 2D cell culture has been widely used, 3D models, especially spheroids, provide better predictive value for toxicological risk assessments since they replicate complex cellular interactions more accurately.
Bianca Montenegro   +5 more
wiley   +1 more source

Subchronic Exposure to Arsenic and Nickel Triggers Nitrosative Stress and Histological Alterations in the Rat Liver

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima   +4 more
wiley   +1 more source

Safety Assessment and Hypoglycemic Effect of Moringa oleifera Lam. Seed Lectin (WSMoL) in Alloxan‐Induced Diabetic Mice

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Moringa oleifera Lam. seeds contain WSMoL, a lectin previously studied for toxicity and pharmacological effects. In this study, we investigated WSMoL (10, 25, or 50 mg/kg i.p.) for acute and 14‐day repeated‐dose toxicity, as well as genotoxicity, in Swiss mice.
Alícia Natalie Silva dos Santos   +10 more
wiley   +1 more source

A tecnologia digital na evolução da BD

open access: yes, 2021
This master's dissertation has the evolution of Comics as the main focus. It explores not only its history, but also its mutations at the narrative level, used supports and how these new potentialities are changing the paradigms as we know them today.In the theoretical component of this project, firstly, we will approachthe path that the visual ...
openaire   +1 more source

Revisiting the Intellectual Legacy of H. Igor Ansoff: A Critical Analysis of His Contributions and Their Impact on the Evolution of Strategic Management

open access: yesStrategic Change, EarlyView.
ABSTRACT This systematic review examines how H. Igor Ansoff's theoretical contributions have evolved in contemporary strategic management through cluster analysis of 116 publications (1968–2024). Four distinct research clusters were identified, revealing that Ansoff's legacy has shifted from theoretical foundations to pedagogical applications and ...
Adiemir Hortega   +4 more
wiley   +1 more source

Electrospun encapsulation of grape pomace extract: in vitro antioxidant, anti‐inflammatory, and antihyperglycemic properties

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The escalating prevalence of lifestyle‐ and aged‐related conditions, including diabetes, chronic inflammation, and cardiovascular disorders, underscores the urgent need for natural therapies. Such alternatives should offer reduced side effects compared to conventional pharmaceuticals while playing a proactive role in disease ...
Estefani Tavares Jansen   +6 more
wiley   +1 more source

Percepções docente quanto ao uso de TDIC em contexto educacional

open access: yesRevista de Estudos e Pesquisas sobre Ensino Tecnológico
A pesquisa realizada no Instituto Federal de Goiás teve como objetivo investigar o uso das Tecnologias Digitais de Informação e Comunicação (TDIC) pelos professores dessa instituição.
Leizer Fernandes Moraes   +1 more
doaj  

Savory biscuits formulated with mixed green banana pulp and peel flours: A sustainable approach to enhance nutritional, technological and sensory properties

open access: yesJournal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND There is a growing consumer interest in foods that not only provide nutritional value and convenience, but also promote health benefits through regular consumption. In this context, green banana flour has emerged as a promising alternative for innovative product development.
Leonara Martins Viana   +5 more
wiley   +1 more source

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