Results 221 to 230 of about 21,102 (303)

Analysis of energy expenditure and behavioral characteristics in different mouse strains under normal and disease conditions

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Mouse metabolic and behavioral phenotypes are tightly linked to strain, age and disease state, with distinct dysregulation in each disease model, underscoring the need for standardized preclinical experimental conditions. Abstract Background Metabolic and behavioral traits in mice exhibit substantial variability across strains, ages, and disease states,
Jiacheng Zeng   +17 more
wiley   +1 more source

2025 ESC/EACTS valvular heart disease guidelines: practical updates on mitral and tricuspid regurgitation. [PDF]

open access: yesEur Heart J Suppl
Adamo M   +5 more
europepmc   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Modeling Catheter‐Associated Bladder Mucosal Adhesion and Microtrauma Using a Human Urothelial Microtissue Model

open access: yesAdvanced NanoBiomed Research, EarlyView.
Intermittent catheter use can damage the urinary tract and predispose to infection. We deployed a complex human urothelial model to investigate. Catheter contact induced compressive and shear stress causing umbrella cell disruption, reduced barrier function, inflammation and increased cell adhesion to the catheter surface.
Nazila V. Jafari, Jennifer L. Rohn
wiley   +1 more source

Structural and Functional Siderophore Remodeling by Enzymatic Delipidation

open access: yesAngewandte Chemie, EarlyView.
A surprising functional switch in bacterial siderophores was discovered through genome mining and the analysis of environmental and pathogenic Pandoraea species. Pandorachelin B, a lipocyclopeptide that promotes swarming motility, is cleaved by a specialized acylase, yielding a ring‐contracted, homodetic cyclopeptide, pandorachelin A, which exhibits ...
Elena Herzog   +5 more
wiley   +1 more source

Magnetic‐Field‐Enabled Ultrafast Quench Synthesis of Single‐Atom Catalysts for Efficient Anion Exchange Membrane Water Electrolysis

open access: yesAngewandte Chemie, EarlyView.
We report a universal magnetic‐field‐enabled quench strategy for the ultrafast synthesis of diverse single‐atom catalysts within seconds. This simple and low‐cost method yields highly active catalysts with excellent performance in anion exchange membrane water electrolysis. ABSTRACT Single‐atom catalysts (SACs) play a critical role in diverse catalytic
Shenghua Chen   +12 more
wiley   +1 more source

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