Results 111 to 120 of about 654,292 (325)

Semiotika Teks: Sebuah Pendekatan Analisis Teks

open access: yesMediaTor, 2004
Semiotika mempelajari relasi elemen-elemen tanda di dalam sebuah sistem berdasarkan aturan main dan konvensi tertentu, serta mengkaji peran tanda sebagai bagian dari kehidupan sosial. Semiotika teks adalah cabang semiotika, yang secara khusus mengkaji teks dalam berbagai bentuk dan tingkatannya.
openaire   +1 more source

CHB‐Induced Immune Zonation Chaos Elicited LXRα‐mediated Lipid Metabolism Disorders in Kupffer Cells to Induce Cancer Stem Cell Formation

open access: yesAdvanced Science, EarlyView.
By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi   +18 more
wiley   +1 more source

The pharmacological research of Tek-1 relevance to anti-neuroinflammation, a candidate compound based on Telmisartan

open access: yesOpen Medicine, 2015
In this paper, BV-2 mouse small glial cell inflammation model induced by LPS is established. The experiment used 0.1-10 μM of telmisartan and Tek-1 to incubate with small glial cell and used telmisartan and Tek-1 to incubate with PPAR gamma special ...
Yang Jianbo, Cui Changcong
doaj   +1 more source

The Gut Microbiota Regulates Motor Deficits via Butyrate in a Gnal+/− Mouse Model of DYT25 Dystonia

open access: yesAdvanced Science, EarlyView.
The present study provides compelling evidence for a modulatory role of the gut microbiota in the pathology of DYT25 dystonia, and butyrate supplementation alleviates the motor deficits of dystonia in Gnal+/− mice. Abstract Dystonia is the third most common movement disorder, following essential tremor and Parkinson's disease. The underlying mechanisms
Jingya Guo   +3 more
wiley   +1 more source

Toba Tek Singh

open access: yesEstudios de Asia y África, 1995
Traducción del urdu: Uma ...
Saadat Hasan Manto, Uma Thukral
doaj  

Combined Photothermal and mTOR‐Targeted Therapy Overcomes Immune Evasion and Enhances Checkpoint Blockade Efficacy in Metastatic Triple‐Negative Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study reveals that photothermal therapy, while inducing immunogenic cell death in triple‐negative breast cancer, paradoxically activates the oncogenic mTOR pathway to drive immune evasion. To counter this, a smart nanocomposite is engineered to co‐deliver localized hyperthermia and mTOR inhibition.
Yujie Zhao   +13 more
wiley   +1 more source

Naltrexone HCI/bupropion HCI for chronic weight management in obese adults: patient selection and perspectives

open access: yesPatient Preference and Adherence, 2016
Cenk Tek Department of Psychiatry, Yale University School of Medicine, New Haven, CT, USA Abstract: Naltrexone, an opiate antagonist, and bupropion, a noradrenergic/dopaminergic antidepressant, have many effects on the reward systems of the brain.
Tek C
doaj  

Eko-Tek Kent Modelinde İç Mekan Tasarımı

open access: yesIDA: International Design and Art Journal, 2020
Ekoloji ve teknoloji kavramlarının birleşimlerinden oluşan eko-tek tasarım anlayışı, günümüz tasarım stratejilerinin çevre sorunlarına mekân ölçeğinde bir çözüm getirememesi sebebiyle ihtiyaç olarak doğmuştur.
Selin ALICI
doaj  

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