Results 131 to 140 of about 108,041 (265)

Phenotypic, physicochemical, sensory, and functional attributes of cocoa (Theobroma cacao L.) from Brazilian Amazonian floodplain and upland ecosystems

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Cocoa (Theobroma cacao L.) from the Brazilian Amazon plays an important role in national production. While most cocoa is cultivated in upland systems, floodplain ecosystems represent a traditional and distinct production environment that may influence bean composition and quality.
Danielle Amaral e Silva, Consuelo Lúcia Sousa de Lima, Giulia Victória Silva Lima, Angela Maria Miranda Silva, Neirivaldo Cavalcante da Silva, Hervé Louis Ghislain Rogez, Jesus Nazareno Silva de Souza   +6 more
wiley   +1 more source

Endothelial-specific Ezh2 deficiency exacerbates blood-brain barrier dysfunction and neuroinflammation in sepsis-associated encephalopathy. [PDF]

J Neuroinflammation
Zhu H, Sun Q, Wang Y, Hu X, Pan Y, Huang T, Xu S, Mu L, Wang Y, Tong M, Tang Y, Luo Z, Yang B, Hou M, Chen Y, Chen Y, Su X, Xu X, Wang Z, Cao M, Xue C.   +20 more
europepmc   +1 more source

Fat Mass and Obesity‐Associated Protein Contributes to Tumorigenesis and Drug Resistance of Diffuse Large B‐Cell Lymphoma by Suppressing N6‐Methyladenosine Methylation of Myc

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu, Jin‐Hao Chen, Yan‐Fang Wang, Xiao Wu, Hui‐Yun Ni, Qiu‐Rong Zhang   +5 more
wiley   +1 more source

Identification of pathological CD133+ endothelial cells in venous malformations. [PDF]

Front Cardiovasc Med
Shawber CJ, Clapp A, Shapiro-Franklin N, Yang S, Harvill MG, Iaconetti E, Schonning MJ, Zeiler AI, Perez M, Koh S, Alkelai A, Wu JK.   +11 more
europepmc   +1 more source

Valproic Acid Inhibits Ferroptosis and Improves Bone Integration in OVX Rats Through the AMPK/SIRT1 Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The prevalence of postmenopausal osteoporosis (PMOP) has been steadily increasing. Ferroptosis has been recognized as a critical factor influencing the bone‐forming ability of bone marrow mesenchymal stem cells (BMSCs). Valproic acid (VPA), an HDAC inhibitor, has been suggested to play a role in regulating osteoporosis development; however ...
Qing‐Song Gu, Yi‐Fan Gu, Jian‐Qiao Li, Yi‐Heng Li, Yu‐Hu Chen, Lin‐Hui Wang, Zi‐Ru Wang, Yi‐Cong Wang, Min Yang   +8 more
wiley   +1 more source

Modulation of the Receptor Tyrosine Kinase TIE2/<i>Tek</i> Pathway by NRF2 Activation in Neurovascular Endothelial Cells. [PDF]

Int J Mol Sci
Cazalla E, García-Yagüe ÁJ, Pajares M, Jiménez-Villegas J, Escoll M, Rojo AI, Cuadrado A.   +6 more
europepmc   +1 more source

RBMX Transcriptionally Repressed by EZH2‐Associated H3K27me3 Modification Attenuates Pyroptosis in Renal Ischemia/Reperfusion Injury via Regulating SIRT3/NLRP3 Inflammasome Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ischemic reperfusion injury (IRI) to kidney is a significant clinical factor in acute kidney injury (AKI). This study aimed to investigate the new role of RNA‐binding motif protein X‐linked (RBMX), a modulator of m6A methylation, in renal IRI and to examine the associated regulatory mechanisms. An in vitro renal IRI model was established using
Yi‐Han Wang, Yan Teng, Fang‐Lan Yao, Shu‐Qi Wei, Yan Li   +4 more
wiley   +1 more source

Vascular basement membrane laminins modulate functional zonation of cerebral microvessels. [PDF]

J Cereb Blood Flow Metab
Deshpande T, Kapupara K, Hannocks MJ, Huppert J, Samawar SK, Thulichery DR, Budny S, Ghavampour S, Song J, Meng L, Adams RH, Jeong HW, Wachsmuth L, Faber C, Soltwisch J, Hallmann R, Sorokin L.   +16 more
europepmc   +1 more source

Endothelial Hydrogels Improve Microvascular Regeneration and Perfusion in Tracheal Scaffolds

The Laryngoscope, EarlyView.
Insufficient vascularization remains a major barrier to successful tracheal transplantation. This study demonstrates that an endothelial hydrogel significantly enhances graft perfusion and neovessel organization compared to non‐endothelial hydrogel controls.
Molly O. Hunter, Lumei Liu, Nathaniel Hochuli, Olivia Chan, Jazmin Calyeca, Ada C. Sher, Tendy Chiang   +6 more
wiley   +1 more source

Citizen Science and Traditional Ecological Knowledge—Values of Inclusion in the Wabanaki Youth Science Program

Maine Policy Review, 2017
tish carr, Darren Ranco
doaj