Results 171 to 180 of about 654,292 (325)

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

open access: yesAdvanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling   +17 more
wiley   +1 more source

Social inequality in the civil service and a review of affirmative action in Nepal

open access: yesThe South Asianist, 2016
This article is a study of the disadvantaged groups in Nepal, namely Janajatis, Madhesis, Dalits, and women; groups that have experienced exclusion in the state’s apparatus since the mid-18th century unification period. By analysing the representation of
Tek Bahadur Dong
doaj  

Catalyst Layer Modifications for Enhanced Performance of Fluorine‐Free Proton Exchange Membrane Fuel Cells

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
Considerable improvement in the performance of fully‐hydrocarbon‐based fuel cells is necessary to replace and compete with Per‐ and polyfluoroalkyl substances‐containing fuel cells. Herein, a way to enhance the ionic conductivity of the catalyst layer (CL) by incorporating insoluble ionomer particles into the CL is presented.
Emmanuel Balogun   +7 more
wiley   +1 more source

Advancing Direct Alcohol Fuel Cells: Innovations in Composite‐Based Electrocatalysts and Polymer Support Materials for Enhanced Efficiency

open access: yesAdvanced Energy and Sustainability Research, EarlyView.
This graphical abstract emphasizes the working principle and the various essential factors of the direct methanol fuel cell (DMFCs). Additionally, various parameters, such as the nanoparticle's size and shape, the nature of the electrolyte, the type of support materials, and their fabrication process, also play essential roles in the functioning of the
Kirti Mishra   +3 more
wiley   +1 more source

Sub‐Micrometer‐Precision Path Following of Piezo‐Actuated Mobile Robot

open access: yesAdvanced Intelligent Systems, EarlyView.
This article reports on the Holonomic‐Beetle (HB), a palm‐sized robot that achieves sub‐micrometer (sub‐µm) precision path tracking across spatial ranges from 100 µm to 10 mm. Using proportional‐integral‐derivative (PID) control, the HB accurately tracks both complex and straight paths with sub‐µm path errors, surpassing existing robots.
Eiji Kusui   +9 more
wiley   +1 more source

Differential roles of EA‐TRAPed cells in the anterior cingulate cortex across various intervention times in inflammatory pain

open access: yesAnimal Models and Experimental Medicine, EarlyView.
The cumulative effect of EA analgesia is partially attributed to the activation of EA‐TRAPed cells in ACC. Multiple EA sessions and single EA sessions activated different neuronal populations in the ACC. The enhanced analgesic effect of multiple EA sessions may be attributed to an increase in the proportion of GABAergic neurons within the ACC. Abstract
Zi Guo   +8 more
wiley   +1 more source

Modulation of the Receptor Tyrosine Kinase TIE2/<i>Tek</i> Pathway by NRF2 Activation in Neurovascular Endothelial Cells. [PDF]

open access: yesInt J Mol Sci
Cazalla E   +6 more
europepmc   +1 more source

Trametinib in Adults with Neurofibromatosis Type 1‐Related Symptomatic Plexiform Neurofibromas

open access: yesAnnals of Neurology, EarlyView.
Objective Mitogen‐activated protein kinase kinase inhibitors have shown promising results in treatment of plexiform neurofibromas in neurofibromatosis type 1 patients, but data in adults are limited. The aim of this phase 2 study was to investigate the efficacy and safety of trametinib in adults with neurofibromatosis type 1.
D. Christine Noordhoek   +7 more
wiley   +1 more source

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