Results 71 to 80 of about 276,558 (254)

Deep Learning‐Driven Discovery and Engineering of an Efficient PETase for Depolymerization and Detoxification of PET Microplastics Under Physiological Conditions

Advanced Science, EarlyView.
A deep learning–driven pipeline mining 246 million protein sequences uncovers AhPETase, an evolutionarily distinct PET hydrolase. Engineered variant AhPETaseM1 degrades post‐consumer PET microplastics under physiological conditions and reverses microplasticinduced cytotoxicity in human lung and colon cells, establishing enzymatic microplastic ...
Yuxuan Wang, Shijie He, Yuheng Chang, Sheng Mao, Jianan Canal Li, Binbin Chen, Hongxun Gao, Mingchun Xu, Chenxu Liu, Yajie Wang   +9 more
wiley   +1 more source

Considerations for culturally sensitive traditional ecological knowledge research in wildlife conservation

Wildlife Society Bulletin, 2018
Traditional Ecological Knowledge (TEK) is increasingly being applied in the field of wildlife conservation, yet conceptualizations of what TEK is and views regarding whether TEK is science remain diverse and, at times, conflicting in the TEK discourse ...
Seafha C. Ramos
doaj   +1 more source

Perceptions of the value of traditional ecological knowledge to formal school curricula: opportunities and challenges from Malekula Island, Vanuatu

Journal of Ethnobiology and Ethnomedicine, 2011
Background The integration of traditional ecological knowledge (TEK) into formal school curricula may be a key tool for the revitalisation of biocultural diversity, and has the potential to improve the delivery of educational objectives.
McCarter Joe, Gavin Michael C
doaj   +1 more source

Compact 9dBEs Enable Efficient and Precise Genome Editing in Mammalian Cells and In Vivo

Advanced Science, EarlyView.
As a compact type II‐D system, the Cas9d‐based platform holds great potential for in vivo applications. Through rational engineering, its derived base editors (9dBEs) enable efficient disease modeling while facilitating single‐vector AAV delivery for in vivo genome editing. These miniature tools offer a robust strategy for basic research and biomedical
Qingquan Xiao, Zhijin Tian, Luqi Weng, Kun Xu, Dingyi Han, Zhaowei Wu, Junnan Li, Shangpu Li, Qijing Zhang, Xiaohui Zhao, Guoling Li, Yinghui Wei, Zhen Gu   +12 more
wiley   +1 more source

Mediasten Hastalıklarında Tek İnsizyon Video Yardımlı Torakoskopik Cerrahi: Tek Merkezli Bir Çalışma

Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi, 2019
Giriş: Videoyardımlı torakoskopik cerrahi (VATS), hasta akıbetinde kanıtlanmışiyileşmeler sağladığından sonon yılda tüm dünyada yaygın bir popülerlikkazanmıştır.
Gökhan Ergene, H.semih Halezeroğlu, Erdal Okur, Mehmet Polat Demirhas, Fatma Tokat   +4 more
doaj   +1 more source

Mimar Vedat Tek [PDF]

, 2015
Mimar Vedat Tek, Osmanlı İmparatorluğunun son dönemlerinde mimarlık mesleğini icra eden ve hepimizin aşina olduğu önemli eserler veren bir ustadır.
Ebru, Eynallı, Erdoğan, Ümmügülsüm
core  

Serial Molecular‐Microstructural Multimodal Intravascular Imaging of Atherosclerotic Plaques in Mice

Advanced Science, EarlyView.
A novel longitudinal molecular and microstructural intravascular imaging approach is developed to study murine atherosclerosis. The technique combines a unique surgical model with a miniaturized multimodal device to detect macrophage activity and lipid simultaneously.
Jiawen Li, Joanne T. M. Tan, Lei Xiang, Jiandi Liu, Ayla Hoogendoorn, Victoria A. Nankivell, Lauren Sandeman, Richard Le, Rouyan Chen, Robert A. McLaughlin, Peter J. Psaltis, Johan W. Verjans, Christina A. Bursill   +12 more
wiley   +1 more source

Randomized preclinical study of machine perfusion in vascularized composite allografts

BJS (British Journal of Surgery), EarlyView., 2020
This study was designed to identify the optimum machine perfusion parameters for preservation of limbs before transplantation, and determine whether this was better than cold storage. Normothermic machine perfusion at a pressure of 70 mmHg (NMP‐70) provided superior preservation to cold storage after transplantation.
K. R. Amin, J. P. Stone, J. Kerr, A. Geraghty, L. Joseph, A. Montero‐Fernandez, J. K. Wong, J. E. Fildes   +7 more
wiley   +1 more source

Increased Disarray of Extracellular Matrix Collagen‐I Fiber Network and Compromised Biomechanics in Aortae From Marfan‐Syndrome Mice Assessed Through Combined Opto‐Biomechatronics

Advanced Science, EarlyView.
Combined structure‐function assessment in aortic rings from Marfan mice using MechaMorph Opto‐Biomechatronics technology relates increased elasticity (stiffness) and dynamic viscosity and less ordered extracellular matrix 3D‐structure (collagen) as potential causes for impaired Windkessel function and compromised haemodynamics in Marfan's syndrome ...
Dominik Schneidereit, Anika Nagel, Vanessa I. T. Zwaans, Laureen Schurr, Jonas Ahr, Michael Haug, Anna Piluso, Alexandra Sporkova, Matthias Karck, Andreas H. Wagner, Oliver Friedrich   +10 more
wiley   +1 more source

Nevruz ve Günlerle İlgili Çağatayca Yazılmış Bir Metin Üzerine Değerlendirme

Uluslararası Uygur Araştırmaları Dergisi, 2019
Halk inanışları içerisinde günlerin önemli bir yeri vardır. Çok eski zamanlardan itibaren insanoğlu günlere özel anlamlar yüklemiş ve günleri karşılaştığı olumlu ya da olumsuz durumların sebebi olarak görmüş, yaşadığı iyi veya kötü şeyleri günlerle ...
Recep TEK
doaj