Results 201 to 210 of about 394,251 (311)

Fat Mass and Obesity‐Associated Protein Contributes to Tumorigenesis and Drug Resistance of Diffuse Large B‐Cell Lymphoma by Suppressing N6‐Methyladenosine Methylation of Myc

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ibrutinib resistance remains a major obstacle in the treatment of diffuse large B‐cell lymphoma (DLBCL). Fat mass and obesity‐associated protein (FTO) has been implicated in drug resistance through its regulation of N6‐methyladenosine (m6A) modifications; however, whether FTO mediates ibrutinib resistance in DLBCL remains unclear.
Ting‐Ting Lu   +5 more
wiley   +1 more source

Strong Teens for Healthy Schools: Protocol for evaluating a youth nutrition, physical activity, and civic engagement protocol. [PDF]

open access: yesFront Public Health
MacMillan Uribe AL   +7 more
europepmc   +1 more source

HAK DiNiN TEK OLUŞU

open access: yesFırat Üniversitesi İlahiyat Fakültesi Dergisi, 2006
Belief and worshipping are needs which were placed in the nature of mankind. Science and intelligence support this fact. Therefore hurnanbeing is a religios being in nature. In fact "the fitrat" (origination) means "sympatizing divine religion". The religion was set by Allah and it belongs to Him.
openaire   +3 more sources

Valproic Acid Inhibits Ferroptosis and Improves Bone Integration in OVX Rats Through the AMPK/SIRT1 Pathway

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The prevalence of postmenopausal osteoporosis (PMOP) has been steadily increasing. Ferroptosis has been recognized as a critical factor influencing the bone‐forming ability of bone marrow mesenchymal stem cells (BMSCs). Valproic acid (VPA), an HDAC inhibitor, has been suggested to play a role in regulating osteoporosis development; however ...
Qing‐Song Gu   +8 more
wiley   +1 more source

Indirect Detection of the Protons in and around Biradicals and their Mechanistic Role in MAS-DNP. [PDF]

open access: yesJ Phys Chem Lett
Chatterjee S   +4 more
europepmc   +1 more source

RBMX Transcriptionally Repressed by EZH2‐Associated H3K27me3 Modification Attenuates Pyroptosis in Renal Ischemia/Reperfusion Injury via Regulating SIRT3/NLRP3 Inflammasome Activation

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ischemic reperfusion injury (IRI) to kidney is a significant clinical factor in acute kidney injury (AKI). This study aimed to investigate the new role of RNA‐binding motif protein X‐linked (RBMX), a modulator of m6A methylation, in renal IRI and to examine the associated regulatory mechanisms. An in vitro renal IRI model was established using
Yi‐Han Wang   +4 more
wiley   +1 more source

On the Origin of the Brain Semi‐Heavy Water Deuterium MR Signal Following Administration of Deuterated Metabolic Substrate: A Cautionary Tale

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose To evaluate the extent to which the appearance of HOD in the brain following systemic administration of a deuterated substrate is due to local brain metabolism versus body metabolism. Methods [6,6‐2H2]glucose, which is transported across the blood‐brain barrier (BBB), and [6,6‐2H2]fructose (Fruc), which does not cross the BBB, were ...
Joseph J. H. Ackerman   +5 more
wiley   +1 more source

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