Results 51 to 60 of about 177,116 (201)

Rare Bleeding Disorders and Bleeding Disorder of Unknown Cause: Current Understanding and Recent Developments

Haemophilia, EarlyView.
ABSTRACT Rare bleeding disorders (RBDs) represent a diverse group of inherited conditions involving coagulation factors or platelets. These conditions, such as Glanzmann thrombasthenia (GT) or severe coagulation factor deficiencies, are uncommon. In contrast, bleeding disorder of unknown cause (BDUC) is a diagnosis of exclusion without an identifiable ...
Alessandro Casini, Robert Klamroth, Bauke Haisma, Dino Mehic, Saskia E. M. Schols   +4 more
wiley   +1 more source

Male genital lichen sclerosus

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Male genital lichen sclerosus is driven by chronic, occluded exposure of susceptible genital epithelium to urine, rather than infection or autoimmunity. This review synthesizes clinical, anatomical and molecular evidence showing how microincontinence and occlusion initiate inflammation, fibrosis and carcinogenesis, and explains the curative effect of ...
Georgios Kravvas, Rory Barry, Richard E. Watchorn, Christopher B. Bunker   +3 more
wiley   +1 more source

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

EHA Endorsement of the Second International Guidelines for the Diagnosis and Management of Hereditary Hemorrhagic Telangiectasia. [PDF]

, 2021
Hereditary hemorrhagic telangiectasia (HHT), also known as Osler-Weber-Rendu disease, is a relatively common “rare” vascular disease with an estimated prevalence of 1 in 5000–8000.1,2 Inheritance is autosomal dominant.
Iris Baumgartner, Rössler, Jochen Karl, Baumgartner, Iris, Johanna A. Kremer Hovinga, Jochen Rössler, Rößler, Jochen, Kremer Hovinga, Johanna A.   +6 more
core   +2 more sources

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, Volume 78, Issue 10, Page 1449-1466, October 2026.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source

Arteriovenous Malformations in Hereditary Haemorrhagic Telangiectasia

Acta Médica Portuguesa, 2014
Keywords: Arteriovenous Malformations; Telangiectasia, Hereditary Hemorrhagic; Tomography, X-Ray Computed.
Klaus Loureiro Irion, Giordano Rafael Tronco Alves   +1 more
doaj   +1 more source

Systemic Bevacizumab for Severe Bleeding From Acquired Gastrointestinal Vascular Malformations

American Journal of Hematology, Volume 101, Issue 10, Page 2605-2615, October 2026.
Targeted antiangiogenic therapy with systemic bevacizumab for bleeding from acquired GI VMs was found to be safe and effective for chronic and severe bleeding from acquired vascular malformations due to idiopathic angiodysplasia, chronic liver disease, and deficiencies of von Willebrand factor, in a patient population comprised mostly of heavily ...
Nardeen E. Ayad, Jacob R. Anderson, Bimalangshu Dey, Rebecca Karp Leaf, Andrew B. Song, Hanny Al‐Samkari   +5 more
wiley   +1 more source

CLINICAL APPROACH TO HEREDITARY HEMORRHAGIC TELANGIECTASIA [PDF]

Journal of IMAB, 2013
Background: Hereditary hemorrhagic telangiectasia (HHT or Rendu-Osler-Weber disease) is a rare syndrome, inherited as an autosomal dominant trait with incidence of 1/10000.
Mary Hachmeriyan, Nikolai Sapundzhiev, Miglena Georgieva, Nataliq Dobrudjanska, Venislav Stoyanov, Dimitrina Konstantinova, Lyudmila Angelova   +6 more
doaj   +1 more source

Septal Release: A Targeted Surgical Strategy for Recurrent Epistaxis

Eye &ENT Research, Volume 3, Issue 3, Page 163-167, September 2026.
ABSTRACT Background Recurrent epistaxis is a common pediatric condition that is typically managed with conservative therapies, but a subset of patients require surgical intervention after treatment failure. We seek to describe the efficacy of septal release for refractory pediatric epistaxis patients. Objective To compare outcomes of septal release for
Alexandra Welschmeyer, Daniel Karasik, Christopher L. Crafton, Eve Tranchito, Sarah Ridge, Cyrus C. Rabbani, Jay Shah   +6 more
wiley   +1 more source

MitraClipTM implantation plus left atrial appendage occlusion in a hereditary hemorrhagic telangiectasia patient

, 2022
Hereditary hemorrhagic telangiectasia is regarded as a high hemorrhagic risk condition, and the management of anticoagulation and heart surgery in these patients can be challenging.
Nestola, P. L., D'Alessandro, P., Bortone, A. S., Tritto, R., Pepe, M., Cillis, E. D., Acquaviva, T., Giordano, A.   +7 more
core   +1 more source