Results 61 to 70 of about 6,792 (211)
Hereditary hemorrhagic telangiectasia: An informative review
Iraqi Journal of Hematology, 2020 Inherited hemorrhagic telangiectasia (HHT or Osler–Weber–Rendu syndrome) is a hereditary condition characterized by malformations of multiple blood vessels (vascular dysplasia), which may lead to bleeding (hemorrhaging).
Neha Rajpurohit +3 more
doaj +1 more source
Transforming growth factor-beta receptor mutations and pulmonary arterial hypertension in childhood
, 2005 BACKGROUND: Pulmonary arterial hypertension (PAH) is a potentially fatal vasculopathy that can develop at any age. Adult-onset disease has previously been associated with mutations in BMPR2 and ALK-1.
Haworth, SG +22 more
core +1 more source
Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing
The Journal of Physiology, EarlyView.Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda +5 more
wiley +1 more source
Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source
Case Reports in Pulmonology, 2017 Hereditary hemorrhagic telangiectasia is a rare autosomal-dominant condition affecting visceral blood vessel development. Cerebral and most commonly pulmonary arteriovenous malformations are found in the majority of symptomatic patients.
Carlos Salazar +2 more
doaj +1 more source
Intratumoral Microbiota in Tumor: Current Understandings and Future Perspectives
MedComm, Volume 7, Issue 7, July 2026.Intratumoral bacteria are emerging as active regulators of cancer evolution rather than bystanders. This review outlines how tumor‐resident microbes drive tumor initiation and growth by inducing genomic instability, epigenetic reprogramming, oncogenic signaling, and chronic inflammation, while promoting metastatic spread via invasion, angiogenesis ...
Jiawei Chen +6 more
wiley +1 more source
Hereditary Hemorrhagic Telangiectasia and Myocardial Infarction
, 2016 Hereditary hemorrhagic telangiectasia, also known as Osler–Weber–Rendu syndrome, is an autosomal dominant genetic disorder that leads to epistaxis, gastrointestinal bleeding, iron deficiency anemia, and arteriovenous malformations at the lungs, the liver,
Rodríguez-González, Fayna +2 more
core +1 more source
Gingival and Periodontal Diseases and Conditions in Children and Adolescents: Consensus Report
Journal of Clinical Periodontology, Volume 53, Issue 7, Page 1068-1099, July 2026.ABSTRACT Background The objectives of this Focused Workshop were to update the epidemiology, aetiology, risk factors, diagnosis and management of gingival and periodontal diseases and conditions in children and adolescents, and to explore the applicability of the 2018 Classification in children and adolescents.
Iain Chapple +30 more
wiley +1 more source
Alk1 Signaling in Vascular Development [PDF]
, 2013 Heterozygous loss of the endothelial-specific transforming growth factor-beta (TGF-β) Type 1 receptor, activin receptor-like kinase 1 (ALK1), results in the autosomal dominant disorder, hereditary hemorrhagic telangiectasia type 2 (HHT2), which is ...
Laux, Derek William
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