Molecular docking and molecular dynamics simulation studies of inhibitor candidates against Anopheles gambiae 3-hydroxykynurenine transaminase and implications on vector control. [PDF]
Adedeji EO +6 more
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Aedes aegypti Resistance to Temephos in Argentina
Monitoring of resistance of Aedes aegypti to temephos was implemented in the provinces of Formosa and Misiones, Argentina, as a response to the need to improve the vigilance for the dengue vector in areas of high risk of dengue. Eggs collected in each locality were reared, and susceptibility to temephos was assayed using larval bioassays.
Alejandro Lucia +2 more
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Toxicokinetics of temephos after oral administration to adult male rats
Archives of Toxicology, 2021Temephos (Tem) is the larvicide of choice to control mosquito transmission of dengue, Zika, and chikungunya. The toxicokinetic and toxicological information of temephos is very limited. The aim of this work was to determine the toxicokinetics and dosimetry of temephos and its metabolites.
Mario Figueroa +2 more
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Temephos, an organophosphate larvicide for residential use: a review of its toxicity
Critical Reviews in Toxicology, 2022Temephos (O,O,O',O'-tetramethyl O,O'-thiodi-p-phenylene bis(phosphorothioate)) is a larvicide belonging to the family of organophosphate pesticides used for the control of different vectors of diseases, such as dengue, Zika, chikungunya, and dracunculiasis.
Betzabet Quintanilla Vega +2 more
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Temephos (Abate�) metabolism and toxicity in rats
Archives of Environmental Contamination and Toxicology, 1985In order to clarifyin vivo relationships between the mammalian metabolism and toxicity of temephos, an organophosphate insecticide, activities of acetylcholinesterase and hepatic mixed function oxidases (MFO) were evaluated in adult female Sprague-Dawley rats after acute and subchronic temephos exposures.
P W, Ferguson, P J, Medon, E, Nasri
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Toxicity of the Organophosphorus Pesticide Temephos
Indonesian Journal of Life Sciences, 2019Dengue is a major public health problem in tropical urban areas, not only because it can quickly progress from the mild dengue fever to the deadly dengue hemorrhagic fever, but also because there is no single cure or licensed vaccine available to this day. To control the disease, the World Health Organization has recommended insecticides to control the
Dina Atrasina Satriawan +2 more
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Temephos Collars for Control of Fleas on Dogs and Cats
American Journal of Veterinary Research, 1977SUMMARY Efficacy of polyvinyl chloride collars containing temephos [0,0'-(thiodi-4,1-phenylene) 0,0,0',0'-tetramethyl bis-(phosphorothioate)] was evaluated in dogs and cats against the cat flea (Ctenocephalides felis). Over a period of 42 weeks, collared (treated) and control dogs were experimentally infested with 100 fleas 23 times, and control and ...
N F, Baker, J E, Miller
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Responses of zooplankton andChaoborus to temephos in a natural pond and in the laboratory
Archives of Environmental Contamination and Toxicology, 1988Application of the organophosphorus insecticide temephos to a natural pond in central Minnesota was followed by reduction within 24 hr in all cladocerans, inDiaptomus leptopus and inChaoborus americanus, and increases in cyclopoid copepods, copepod nauplii and the rotiferKeratella cochlearis.
J C, Helgen, N J, Larson, R L, Anderson
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Human Biotransformation Pathway of Temephos Using an In Silico Approach
Chemical Research in Toxicology, 2020Temephos is an organophosphorothioate (OPT) larvicide used for controlling vectors of diseases such as dengue, chikungunya, and Zika. OPTs require a metabolic activation mediated by cytochrome P540 (CYP) to cause toxic effects, such as acetylcholinesterase (AChE) activity inhibition.
Andrés Reyes-Chaparro +2 more
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Effects of temephos on zooplankton communities in enclosures in a shallow eutrophic lake
Environmental Pollution, 1989An organophosphorus insecticide, temephos, was applied to large-volume (105 m3) enclosures set up in a shallow eutrophic lake. Application of the chemical at a target concentration of 500 microg litre(-1) eliminated almost all zooplankters. No recovery of cladocerans was evident at the termination of the experiment (47th day after the treatment ...
T, Hanazato +3 more
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