Results 41 to 50 of about 250,722 (291)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

The psychological-type profile of clergywomen in ordained local ministry in the Church of England : pioneers or custodians? [PDF]

, 2012
This study employs psychological-type theory to compare the psychological profile of 144 clergywomen serving in ordained local ministry in the Church of England alongside the established profile of 237 professional mobile clergywomen serving in the ...
Advisory Board of Ministry, Advisory Board of Ministry, Advisory Board of Ministry, Advisory Council for the Church's Ministry, Baab LM, Butler A, Craig CL, Duncan B, Edwards L, Fowke R, Francis LJ, Francis LJ, Francis LJ, Francis LJ, Francis LJ, Francis LJ, Francis LJ, Goldsmith M, Grant WH, Hind J, Jones SH, Jung CG, Keirsey D, Kendall E, Leslie J. Francis, Malone P, Mandy Robbins, Martinez P, McGuinnes J, Michael CP, Myers IB, Myers IB, Osborn L, Oswald RM, Roberts T, Sanford JM, Susan H. Jones   +36 more
core   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

Annals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold, Krzysztof W. Selmaj, Regina Berkovich, Jeffrey A. Cohen, Giancarlo Comi, Eva K. Havrdová, James K. Sheffield, Hetal Desai, Chun‐Yen Cheng, Jon V. Riolo, Andrew Thorpe, Erik DeBoer, Bruce A. C. Cree   +12 more
wiley   +1 more source

Hyperthymic temperament predicts neural responsiveness for nonmonetary reward

PCN Reports, 2023
Aim Hyperthymic temperament is a cheerful action orientation that is suggested to have a protective effect on depressive symptoms. We recently reported that hyperthymic temperament can positively predict activation of reward‐related brain areas in ...
Yukiko Ogura, Yumi Wakatsuki, Naoki Hashimoto, Tamaki Miyamoto, Yukiei Nakai, Atsuhito Toyomaki, Yukio Tsuchida, Shin Nakagawa, Takeshi Inoue, Ichiro Kusumi   +9 more
doaj   +1 more source

The Temperament Police: The Truth, the Ground Truth, and Nothing but the Truth [PDF]

, 2011
The tuning system of a keyboard instrument is chosen so that frequently used musical intervals sound as consonant as possible. Temperament refers to the compromise arising from the fact that not all intervals can be maximally consonant simultaneously ...
Benetos, E., Dixon, S., Tidhar, D.
core   +1 more source

Temperament-Conscious Humanistic Pedagogy [PDF]

, 2014
Temperament, Humanistic Education, Temperament-Conscious Education, School Grades, Humanistic PedagogyPeer ...
Leino, Mare, Mullola, Sari
core   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and 1‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, EarlyView.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension phase).
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Relationship of Serotonin Transporter Gene Polymorphism With Temperament in Persian Medicine in Fars Province, Iran

Research in Molecular Medicine, 2021
Background: Despite its effectiveness, there are still many concerns and questions about the principles and therapeutic methods of Traditional Medicine (TM).
Shabnam Aliabadi, Zahra Zendehboodi
doaj  

Relationship of horse temperament with breed, age, sex, and body characteristics: a questionnaire-based study

Beni-Suef University Journal of Basic and Applied Sciences, 2021
Background Temperament is an important issue that must be taken into consideration when purchasing horses for leisure, racing, or even work in the fields.
Naglaa M. Abdel-Azeem, H. H. Emeash
doaj   +1 more source

Experimental Evaluation of 100Cr6 Steel Microindented Surfaces Under Lubricated Nonconformal Point Contacts

Advanced Engineering Materials, EarlyView.
The tribological behavior of 100Cr6 steel spheres textured via Vickers microindentation is evaluated under lubricated sliding by varying both dimple size and density. Fine and dense textures significantly reduce friction across all lubrication regimes, while large dimples increase it.
Farideh Davoodi, Pasquale Guglielmi, Gianfranco Palumbo, Giuseppe Carbone   +3 more
wiley   +1 more source