Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Early environment and neurobehavioral development predict adult temperament clusters. [PDF]
Investigation of the environmental influences on human behavioral phenotypes is important for our understanding of the causation of psychiatric disorders.
Eliza Congdon +14 more
doaj +1 more source
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold +12 more
wiley +1 more source
Exploring the Links Between Parental Attachment Style, Child Temperament and Parent-Child Relationship Quality During Adolescence [PDF]
Linked with a myriad of developmental outcomes, the parent-child relationship serves an important function, and it is therefore important that determinants of this relationship are elucidated so that optimal outcomes can be promoted.
Walsh, G., Zadurian, N.
core +1 more source
Effect of the temperament of dairy cows on lifetime production efficiency [PDF]
The aim of this study was to analyse the effect of the temperament of cows on their lifetime production efficiency. Data on milk performance, longevity and culling reasons of 11 629 Polish Holstein-Friesian cows were extracted from the SYMLEK database ...
W. Neja +4 more
doaj +1 more source
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
Hopelessness and temperament of youth in residential treatment [PDF]
Plan BThe importance of hopelessness and temperament within the study of youth psychiatric disorders is becoming increasingly apparent. Analysis of these two constructs further elucidates the factors that are correlated with psychopathology in children ...
McKenney, Jackie
core
Habitat stability and predation pressure affect temperament behaviours in populations of three-spined sticklebacks [PDF]
1. There is growing interest in the causes and consequences of animal temperaments. Temperament behaviours often have heritable components, but ecological variables can also affect them. Numerous variables are likely to differ between habitats, and these
Colegrave, Nick +4 more
core +1 more source
Background: Despite its effectiveness, there are still many concerns and questions about the principles and therapeutic methods of Traditional Medicine (TM).
Shabnam Aliabadi, Zahra Zendehboodi
doaj
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song +10 more
wiley +1 more source

