Results 91 to 100 of about 11,612,362 (357)

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

open access: yesFEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang   +2 more
wiley   +1 more source

The Effect of Line of Sight Temperature Variation and Noise on Dust Continuum Observations [PDF]

open access: yesAstrophys.J.696:2234-2251,2009, 2009
We investigate the effect of line of sight temperature variations and noise on two commonly used methods to determine dust properties from dust continuum observations of dense cores. One method employs a direct fit to a modified blackbody SED; the other involves a comparison of flux ratios to an analytical prediction.
arxiv   +1 more source

Finite temperature regularization [PDF]

open access: yes, 2002
We present a non-perturbative regularization scheme for Quantum Field Theories which amounts to an embedding of the originally unregularized theory into a spacetime with an extra compactified dimensions of length L ~ Lambda^{-1} (with Lambda an ...
Adler   +18 more
core   +2 more sources

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Metamagnetic transition in single-crystalline UIr $$_{2}$$ 2 Si $$_{2}$$ 2

open access: yesScientific Reports, 2023
A single crystal of the ternary uranium silicide UIr $$_{2}$$ 2 Si $$_{2}$$ 2 was studied by means of of X-ray diffraction, magnetization, heat capacity and electrical transport measurements.
Maria Szlawska   +3 more
doaj   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

open access: yesFEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp   +5 more
wiley   +1 more source

Energy pseudogaps and structural transitions in metals [PDF]

open access: yesarXiv, 2011
It is shown that a structural transition in a metal is associated with the opening of the energy pseudogap in the electronic spectrum in a low-temperature phase below the transition temperature. A relation between the magnitude of the energy pseudogap in the d-band of transition metals (at zero temperature) and the structural transition temperature is ...
arxiv  

On temperature versus doping phase diagram of high critiical temperature superconductors [PDF]

open access: yes, 1998
The attempt to describe the bell-shape dependence of the critical temperature of high-$T_{c}$ superconductors on charge carriers density is made. Its linear increase in the region of small densities (underdoped regime) is proposed to explain by the role ...
Loktev, V. M., Turkowski, V. M.
core   +4 more sources

Brucella NyxA and NyxB dimerization enhances effector function during infection

open access: yesFEBS Letters, EarlyView.
Brucella abortus thrives inside cells thanks to the translocation of effector proteins that fine‐tune cellular functions. NyxA and NyxB are two effectors that destabilize the nucleolar localization of their host target, SENP3. We show that the Nyx proteins directly interact with each other and that their dimerization is essential for their function ...
Lison Cancade‐Veyre   +4 more
wiley   +1 more source

Kondo Temperature and High to Low Temperature Crossover in Quantum Dots [PDF]

open access: yesarXiv, 2019
Kondo temperature is standardly defined from the local zero-temperature susceptibility in the regime of strong electron correlations as a new scale controlling the low-temperature asymptotics of thermodynamic quantities. We show by using a two-particle self-consistent theory that the Kondo temperature can be identified as a crossover temperature at ...
arxiv  

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