Results 111 to 120 of about 2,364,234 (301)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

Unusual effects of anisotropy on the specific heat of ceramic and single crystal MgB2

open access: yes, 2002
The two-gap structure in the superconducting state of MgB_2 gives rise to unusual thermodynamic properties which depart markedly from the isotropic single-band BCS model, both in their temperature- and field dependence. We report and discuss measurements
A. Junod   +74 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Microstructure and Doping/Temperature-Dependent Photoluminescence of ZnO Nanospears Array Prepared by Hydrothermal Method

open access: yesNanoscale Research Letters, 2018
Al-doped ZnO nanospears were prepared by a hydrothermal method. The crystalline structure and photoluminescence properties of ZnO nanospears were characterized for investigating the effect of Al doping on the properties of ZnO nanospears.
Shiwei Shi   +3 more
doaj   +1 more source

Real space analysis of inherent structures

open access: yes, 2004
We study a generalization of the one-dimensional disordered Potts model, which exhibits glassy properties at low temperature. The real space properties of inherent structures visited dynamically are analyzed through a decomposition into domains over ...
Bray A. J.   +8 more
core   +5 more sources

characteristic temperatures

open access: yes
Citation: 'characteristic temperatures' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12746 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Test and Simulation of the Axial Temperature Rise Characteristic of AMT Clutch Pressure Plate

open access: yesJixie chuandong, 2016
The AMT clutch pressure plate temperature rise characteristics with different thickness of pressure plate under different working environments are studied.
Long Meiyuan   +5 more
doaj  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Time scale for the onset of Fickian diffusion in supercooled liquids

open access: yes, 2005
We propose a quantitative measure of a time scale on which Fickian diffusion sets in for supercooled liquids and use Brownian Dynamics computer simulations to determine the temperature dependence of this onset time in a Lennard-Jones binary mixture.
B. Doliwa   +4 more
core   +1 more source

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