Results 101 to 110 of about 5,493,355 (296)
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Experimental Evaluation of a 2DOF Controller for a Novel Multi-Temperature Transport System
IEEE AccessMulti-temperature transport systems offer a significant opportunity to improve supply chain efficiency by enabling the simultaneous transport of goods with diverse temperature requirements. However, these systems present critical environmental challenges
Maximilian Losch +2 more
doaj +1 more source
Spacecraft component heater control system [PDF]
A heater control circuit is disclosed as being constructed in a single integrated circuit, with the integrated circuit conveniently mounted proximate to a spacecraft component requiring temperature control.
Bachtel, Frederick D., Owen, James W.
core +1 more source
Frictional experiments of dolerite at intermediate slip rates with controlled temperature: Rate weakening or temperature weakening? [PDF]
, 2011 A rotary shear apparatus has been newly set up in Chiba University which can control the temperature near a sliding surface, T_meas, up to 1000°C independently from slip rate, V.
Hirose, Takehiro +3 more
core
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Системный анализ и прикладная информатикаThe moistening of raw cotton and cotton fiber is a critical stage in the textile production process, significantly influencing the quality of the final product. However, achieving optimal moisture content presents numerous challenges.
Z. U. Ortiqov
doaj +1 more source
Design considerations for thermostatic fin spacecraft temperature control [PDF]
Design considerations for thermostatic fin spacecraft temperature ...
Kneissl, G. J. +2 more
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
EnergiesTo further enhance the economic performance of fuel cell vehicles (FCVs), this study develops a model-adaptive model predictive control (MPC) strategy.
Qi Jiang +5 more
doaj +1 more source
Radiometric temperature reference [PDF]
, 1969 Radiometric Temperature Reference uses a thermistor as both a heating and sensing element to maintain its resistance at a preselected level to continuously control the power supplying it.
Monford, L. G., Jr.
core +1 more source