Results 171 to 180 of about 5,539,618 (300)

Pharmacotherapeutic Controversies During Temperature Control After Out-of-Hospital Cardiac Arrest: A Semi-Structured Literature Review. [PDF]

Pharmacotherapy
Forehand CC, Benken ST, Madorsky M, Mohamed A, Nguyễn JV, Dixit D, Gallagher J, Hawkins WA, Heavner MS, Johnson E, Lozano L, Sisco M, Slampak-Cindric AA, Smith SE, Spezzano K, Taylor BA, Wayne NB, Gagnon DJ.   +17 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Temperature Control of Nonlinear Continuous Stirred Tank Reactors Using an Enhanced Nature-Inspired Optimizer and Fractional-Order Controller. [PDF]

Biomimetics (Basel)
Ekinci S, Izci D, Almeree A, Tümen V, Gider V, Stoyanov I, Jabari M.   +6 more
europepmc   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Development of a Rice Bread Baking Method via Gelatinization Temperature Control Using Modified Starch. [PDF]

J Appl Glycosci (1999)
Yano H, Murashita K, Sato R, Koda T, Nishioka A.   +4 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Around the <i>ThermoClock</i>: A precision automated temperature control system for Ex Vivo circadian studies. [PDF]

MethodsX
Zhang KK, Locurto D, Belden M, Price M, Kearney CJ, Huber ME.   +5 more
europepmc   +1 more source

Temperature control after cardiac arrest. [PDF]

Resuscitation, 2023
Elmer J, Callaway CW.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Temperature control board design and validation for skipper-CCD sensors using a buck converter. [PDF]

HardwareX
Barrientos M, Barrientos M, Rodas J, Renault A, Romero C, Palacios F, Chavez C, Botti AM.   +7 more
europepmc   +1 more source