Results 51 to 60 of about 5,539,618 (300)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Experimental and numerical study on the chemical reactions of carbon dioxide–air mixtures behind high-speed shock waves

open access: yesAIP Advances
The ablation product carbon dioxide (CO2) around the hypersonic vehicle may become an important source of radiation. Accurate simulation of the chemical reaction process between CO2 and air is of great significance for the design of thermal protection ...
Yixin Xu   +9 more
doaj   +1 more source

Temperature control of a cryogenic bath [PDF]

open access: yes, 1972
Foreign gas introduced into vapor phase above liquid region cools cryogenic baths. Equipment consists of gas tank and cover of styrofoam. Helium is considered the best choice to produce cooling, though any gas with boiling point lower than that of bath ...
Asher, I. M.
core   +1 more source

A Soft Robotic Cover with Dual Thermal Display and Sensing Capabilities [PDF]

open access: yes, 2020
We propose a new robotic cover prototype that achieves thermal display while also being soft. We focus on the thermal cue because previous human studies have identified it as part of the touch pleasantness.
Kheddar, Abderrahmane, Osawa, Yukiko
core   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Energy Consumption Model for Indoor Cannabis Cultivation Facility

open access: yesIEEE Open Access Journal of Power and Energy, 2020
The recent legalization of cannabis is facilitating very rapid growth in the cannabis cultivation industry, with the energy intensive indoor cultivation facilities becoming more prevalent.
Nafeesa Mehboob   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Predicting survival in out-of-hospital cardiac arrest patients undergoing targeted temperature management: The Polish Hypothermia Registry Risk Score

open access: yesCardiology Journal, 2021
BACKGROUND: Prompt reperfusion and post-resuscitation care, including targeted temperature management (TTM), improve survival in out-of-hospital cardiac arrest (OHCA) patients. To predict inhospital mortality in OHCA patients treated with TTM, the Polish
Łukasz Kołtowski   +16 more
doaj   +1 more source

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