Results 111 to 120 of about 15,716,870 (262)

Temperature effect on space charge dynamics in XLPE insulation

open access: yes, 2007
This paper reports on space charge evolution in crosslinked polyethylene (XLPE) planar samples approximately 1.20 mm thick subjected to electric stress level of 30 kVdc/mm under four temperature 25 oC, 50 oC, 70 oC and 90 oC for 24 hours.
Chong, Y L, Chen, G, Ho, Y F F
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Acclimatory response to environmental temperature in two species of marine crab: the stenothermal cancer pagurus and the eurythermal carcinus maenas [PDF]

open access: yes, 1996
Temperature acclimation effects on leg muscle plasma membrane composition and biophysical state, neuromuscular function and whole organism thermal tolerance, and their dependence on the background seasonal acclimatization were investigated in the ...
Cuculescu, Mirela, Cuculescu, M
core  

Simultaneous effects of temperature and backbone length on static and dynamic properties of high-density polyethylene-1-butene copolymer melt: Equilibrium molecular dynamics approach

open access: yese-Polymers
Temperature and chain length play significant roles in determining the physical properties of polymer melts. In the current computational research, a molecular dynamics (MD) approach was implemented to describe the static and dynamic properties of (1 ...
Yazdanbakhsh Amirhosein   +1 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Exploring the effect of temperature variations on unplanned asthma admissions

open access: yes, 2011
Global climate change is one of the highest concerns in the scientific, health and environmental arena. Establishing association between weather and health exposures are fundamental to learn about the complex exposure-disease relationship but the link ...
Demir, E.   +3 more
core  

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