Results 141 to 150 of about 3,130,753 (313)

Tests of predictions made by the Equilibrium Model for the effect of temperature on enzyme activity

open access: yes, 2008
The Classical Model describing the effects of temperature on enzyme activity consists of two processes: the catalytic reaction defined by ΔG cat and irreversible inactivation defined by ΔG inact, this model however, does not account for the observed ...
Oudshoorn, Matthew Leslie
core  

Low-temperature magnetic properties of magnetite

open access: yes, 2000
Although several studies have recommended removal of secondary components of magnetic remanence by zero-field cycling from room temperature to a temperature much lower than the low temperature transition for magnetite (about 120 K), the method has not ...
Wyn Williams   +3 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Fatigue Damage Characteristics of Oil-Well Cement Slurries Under Frequent Cyclic Loading at Various Temperatures

open access: yesApplied Sciences
The rapid development of renewable energy requires the support of large-scale energy storage technologies to maintain system balance. Salt cavern compressed air energy storage (CAES) is regarded as one of the key technological pathways for large-scale ...
Qiqi Ying   +6 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Dynamic mechanical properties and constitutive model of ultra-high performance concrete subjected to coupled high-temperature and impact loading

open access: yesBaozha yu Chongji
In order to investigate the dynamic mechanical properties of ultra-high performance concrete (UHPC) under coupled high-temperature and explosive impact effects, a 75 mm-diameter high-temperature split Hopkinson pressure bar (SHPB) apparatus was employed.
Chen ZHANG   +4 more
doaj   +1 more source

The Effect of Temperature on Bacteriostasis

open access: yesJournal of Pharmacy and Pharmacology, 1955
H, BERRY, J C, PARKINSON
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

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